伊朗乌尔米耶孕妇戊型肝炎血清流行率
Seroprevalence of hepatitis e among pregnant women in urmia, iran.
作者信息
Rostamzadeh Khameneh Zakieh, Sepehrvand Nariman, Khalkhali Hamid-Reza
机构信息
Department of Microbiology and Immunology, Urmia University of Medical Sciences, Urmia, IR Iran.
Students' Research Committee, Urmia University of Medical Sciences, Urmia, IR Iran.
出版信息
Hepat Mon. 2013 Nov 15;13(11):e10931. doi: 10.5812/hepatmon.10931. eCollection 2013.
BACKGROUND
While hepatitis E virus (HEV) mostly causes self-limited disease in general population, it is more severe in pregnant women.
OBJECTIVES
This study aimed to investigate the seroprevalence of anti-HEV IgG among a population of pregnant women in West Azerbaijan of Iran .
PATIENTS AND METHODS
One hundred thirty six pregnant women referred to urban health centers of Urmia for pursuing pregnancy-related health services were enrolled in a descriptive, cross-sectional study. Anti-HEV IgG antibody was evaluated using enzyme-linked immunosorbent assay (enzyme-linked immunosorbent assay, ELISA; Dia.Pro; Diagnostic Bioprobes).
RESULTS
Only five (3.6%) of 136 cases had positive results for anti-HEV IgG. There was no significant difference between age (P=0.88), and income level (P = 0.19) of the two seropositive and seronegative groups. All seropositive cases were from urban areas.
CONCLUSIONS
The seroprevalence of anti-HEV IgG is low in the population of pregnant women in , similar to the rates reported from developed countries. Effective health services and provision of safe water supplies in Urmia may take role in this low prevalence rate.
背景
戊型肝炎病毒（HEV）在普通人群中大多引起自限性疾病，但在孕妇中病情更为严重。
目的
本研究旨在调查伊朗西阿塞拜疆省孕妇人群中抗HEV IgG的血清流行率。
患者和方法
选取136名到乌尔米耶市城市健康中心寻求妊娠相关健康服务的孕妇，纳入一项描述性横断面研究。采用酶联免疫吸附测定法（酶联免疫吸附测定，ELISA；Dia.Pro；Diagnostic Bioprobes）评估抗HEV IgG抗体。
结果
136例中仅有5例（3.6%）抗HEV IgG检测结果为阳性。两个血清阳性组和血清阴性组在年龄（P = 0.88）和收入水平（P = 0.19）方面无显著差异。所有血清阳性病例均来自城市地区。
结论
与发达国家报告的率相似，伊朗西阿塞拜疆省孕妇人群中抗HEV IgG的血清流行率较低。乌尔米耶有效的卫生服务和安全供水的提供可能是导致这一低流行率的原因。
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