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作为代谢综合征独立风险因素的体质:倾向评分匹配分析。

The sasang constitution as an independent risk factor for metabolic syndrome: propensity matching analysis.

机构信息

Department of KM Health Technology Research Group, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 305811, Republic of Korea.

出版信息

Evid Based Complement Alternat Med. 2013;2013:492941. doi: 10.1155/2013/492941. Epub 2013 Nov 20.

Abstract

THE SASANG CONSTITUTIONAL MEDICINE IS A TRADITIONAL KOREAN CUSTOMIZED MEDICINE THAT CLASSIFIES PEOPLE INTO FOUR TYPES

Tae-eumin (TE), Soyangin (SY), Soeumin (SE), and Taeyangin. The aim of this study was to show whether the Sasang Constitution (SC) could be an independent risk factor for the metabolic syndrome (MS). Totally, 3,334 subjects from 24 Korean medicine clinics participated in this study. A one-way ANOVA for the continuous variables and a chi-square test for the prevalence of MS were conducted. A logistic regression was conducted to calculate the propensity score and the odds ratios (ORs). The prevalence for MS in TE, SY, and SE was 50.6%, 30.9%, and 17.7% (P < 0.001) before matching, and 36.7%, 28.6% and 28.2% (P = 0.042) after matching, respectively. The TE was associated with an increased OR for MS compared with the SE and SY in both crude (OR 4.773, 95% CI 3.889-5.859, and OR 2.292, 95% CI 1.942-2.704, resp.) and matched groups (OR 1.476, 95% CI 1.043-2.089, and OR 1.452, 95% CI 1.026-2.053, resp.). This study reveals that the SC, especially the TE type, could be considered as a risk element for MS even in people with otherwise similar physical characteristics.

摘要

四象体质医学是一种传统的韩国定制医学,将人分为四种类型:太乙民(TE)、少阳人(SY)、少阴人(SE)和太阳人(TAE)。本研究旨在探讨四象体质(SC)是否可以作为代谢综合征(MS)的独立危险因素。共有 24 家韩国医学诊所的 3334 名受试者参与了本研究。对连续变量进行单因素方差分析,对 MS 的患病率进行卡方检验。采用 logistic 回归计算倾向评分和比值比(OR)。在匹配前,TE、SY 和 SE 中 MS 的患病率分别为 50.6%、30.9%和 17.7%(P<0.001),匹配后分别为 36.7%、28.6%和 28.2%(P=0.042)。与 SE 和 SY 相比,TE 与 MS 的粗 OR 和匹配 OR 均升高(OR 分别为 4.773、95%CI 3.889-5.859 和 1.476、95%CI 1.043-2.089,OR 分别为 2.292、95%CI 1.942-2.704 和 1.452、95%CI 1.026-2.053)。本研究表明,SC,特别是 TE 型,即使在身体特征相似的人群中,也可被视为 MS 的危险因素之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b36f/3853938/b83946e63b7e/ECAM2013-492941.001.jpg

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