Zhou Yan, Dong Wen, Zou Fangwen, Zhou Dong-Ai, Ma Jin-An
Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.
Oncol Lett. 2014 Jan;7(1):140-144. doi: 10.3892/ol.2013.1649. Epub 2013 Oct 29.
Synovial sarcomas commonly occur in the soft tissue of the extremities, while a primary occurrence in the mediastinum is quite rare. The current study reports the case of an 11-year-old male who presented with a neck mass, which computed tomography showed was due to a giant mediastinal mass involving the thyroid gland. The tumor was resected by thoracotomy and diagnosed as monophasic synovial sarcoma by histopathology. The patient received adjuvant combination chemotherapy and radiation therapy following surgery. At the 3-month follow-up, no local tumor recurrence was found. The present case report highlights the significance of recognizing the unusual presentation and clinical manifestation of synovial sarcoma to aid clinical management. Written informed consent was obtained from the patient's family.
滑膜肉瘤常见于四肢软组织,而原发于纵隔者极为罕见。本研究报告了一例11岁男性患者,该患者颈部出现肿物,计算机断层扫描显示为巨大纵隔肿物累及甲状腺。通过开胸手术切除肿瘤,组织病理学诊断为单相性滑膜肉瘤。患者术后接受了辅助联合化疗和放射治疗。在3个月的随访中,未发现局部肿瘤复发。本病例报告强调了认识滑膜肉瘤不寻常表现和临床表现以辅助临床管理的重要性。已获得患者家属的书面知情同意。