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早孕期血清和尿液中完整人绒毛膜促性腺激素及其游离亚基浓度之间的关系。

Relationship between blood and urine concentrations of intact human chorionic gonadotropin and its free subunits in early pregnancy.

作者信息

Norman R J, Menabawey M, Lowings C, Buck R H, Chard T

出版信息

Obstet Gynecol. 1987 Apr;69(4):590-3.

PMID:2434894
Abstract

Paired blood and urine samples were obtained from patients between the sixth and 14th weeks of normal pregnancy. The levels of intact human chorionic gonadotropin (hCG), and of the free alpha and beta subunits, were measured by specific immunoassays. There was a close association between blood and urine levels of intact hCG and of the alpha subunit of hCG, but no relation between the levels of beta subunit in these sites. These findings suggest that the use of "beta subunit" assays may give discrepant results according to the fluid examined. By contrast, measurement of intact hCG appears to give similar results in blood and urine.

摘要

在正常妊娠的第6至14周期间,从患者身上采集了配对的血液和尿液样本。通过特异性免疫测定法测量了完整人绒毛膜促性腺激素(hCG)以及游离α和β亚基的水平。完整hCG和hCGα亚基的血液和尿液水平之间存在密切关联,但这些部位的β亚基水平之间没有关系。这些发现表明,根据所检测的体液不同,使用“β亚基”检测可能会得出不一致的结果。相比之下,完整hCG的测量在血液和尿液中似乎能得出相似的结果。

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Strips of Hope: Accuracy of Home Pregnancy Tests and New Developments.希望试纸:家用妊娠试验的准确性及新进展
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The association of maternal factors with delayed implantation and the initial rise of urinary human chorionic gonadotrophin.母体因素与延迟着床及人绒毛膜促性腺激素尿初始升高的关系。
Hum Reprod. 2011 Apr;26(4):920-6. doi: 10.1093/humrep/der009. Epub 2011 Feb 2.
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How positive is a positive pregnancy test?验孕呈阳性的准确性有多高?
Br Med J (Clin Res Ed). 1988 Mar 12;296(6624):730-1. doi: 10.1136/bmj.296.6624.730.