血清白细胞介素-18 水平与日本男性的身体活动有关。
Serum interleukin-18 levels are associated with physical activity in Japanese men.
机构信息
Department of Hygiene, Faculty of Medicine, Kagawa University, Kita, Kagawa, Japan.
Department of Hygiene, Faculty of Medicine, Kagawa University, Kita, Kagawa, Japan ; Okayama Southern Institute of Health, Okayama Health Foundation, Kita, Okayama, Japan.
出版信息
PLoS One. 2013 Dec 11;8(12):e81497. doi: 10.1371/journal.pone.0081497. eCollection 2013.
OBJECTIVE
To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men.
METHODS
A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated.
RESULTS
Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = -0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors.
CONCLUSION
Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.
目的
探讨血清白细胞介素-18（IL-18）水平与日本男性体力活动之间的关系。
方法
本横断面研究共纳入 81 名男性（45.7±17.6 岁）。我们评估了人体测量学和身体成分参数。还评估了血清 IL-18 水平、单轴加速度计评估的体力活动、峰值摄氧量和代谢风险参数。
结果
血清 IL-18 水平为 179.4±84.7 pg/mL。Σ[每周代谢当量×小时（METs⋅h/w）]评估的体力活动与血清 IL-18 水平呈显著负相关（r=-0.252，p=0.0235）。即使在校正了峰值摄氧量和其他混杂因素后，这些关联仍然存在。
结论
在日本男性中，血清 IL-18 水平与体力活动密切相关，与峰值摄氧量无关。
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