Misra Kiran B, Endemann Sarah W, Ayer Mandeep
Department of Exercise and Nutritional Sciences, San Diego State University; 5500 Companile Drive, San Diego, CA 92182, USA.
Ethn Dis. 2005 Autumn;15(4):627-34.
Immigrant Asian Indians possess major lipid and non-lipid risk factors that constitute features characteristic of metabolic syndrome. First-line therapy recognized in risk management of this syndrome is weight reduction and increased physical activity. We investigated the relationship of intensity and duration of leisure time physical activity (LTPA) to physiological indices of metabolic syndrome in Asian Indian immigrants.
Fifty-six apparently healthy men (43.7 years +/- 7.1; body mass index [BMI] 21-34) and women (43.1 years +/- 6.9; BMI 21-36) were screened to participate in this cross-sectional study. Leisure time physical activity (LTPA) was determined by Minnesota LTPA questionnaire. Anthropometric measurements were recorded by using standard procedures. Blood samples taken after an overnight fast were analyzed for measures defined by the NCEP ATP III criteria for metabolic syndrome.
Prevalence of metabolic syndrome was 33.9% (age 29-59 years; average BMI 26.1 +/- 3.7) suggesting development of syndrome at younger age. While participants reported little LTPA, men were more active than women (total activity metabolic index (AMI) per week: 533 vs 204, respectively). In men, moderate activity was associated with a lower prevalence of metabolic syndrome, lower fasting glucose (r=-0.44), 2-hour glucose tolerance (r=-0.40), and lower serum triglyceride (r=-0.63). Only heavy activity was inversely associated with waist girth for both men (r=-0.46) and women (r=-0.41). Leisure activity levels reported by women were not significantly associated with any other risk factors. Low levels of physical activity were associated with prevalence of low high-density lipoprotein cholesterol (HDL-C), but reported LTPA levels were not significantly associated with favorable changes in serum HDL-C or blood pressure in both sexes.
We provide evidence that Asian Indians who are physically active have a more favorable metabolic syndrome risk factor profile. Results highlight need to encourage physical activity in Asian Indian immigrants, particularly women, to reduce prevalence of metabolic syndrome.
亚洲印度移民存在主要的脂质和非脂质风险因素，这些因素构成了代谢综合征的特征。该综合征风险管理中认可的一线治疗方法是减轻体重和增加体力活动。我们研究了休闲时间体力活动（LTPA）的强度和持续时间与亚洲印度移民代谢综合征生理指标之间的关系。
筛选了56名明显健康的男性（43.7岁±7.1岁；体重指数[BMI]21 - 34）和女性（43.1岁±6.9岁；BMI 21 - 36）参与这项横断面研究。通过明尼苏达LTPA问卷确定休闲时间体力活动（LTPA）。使用标准程序记录人体测量数据。空腹过夜后采集的血样用于分析符合美国国家胆固醇教育计划成人治疗组第三次报告（NCEP ATP III）代谢综合征标准的指标。
代谢综合征患病率为33.9%（年龄29 - 59岁；平均BMI 26.1±3.7），表明该综合征在较年轻的年龄阶段出现。虽然参与者报告的LTPA很少，但男性比女性更活跃（每周总活动代谢指数（AMI）：分别为533和204）。在男性中，中等强度活动与代谢综合征患病率较低、空腹血糖较低（r = -0.44）、2小时葡萄糖耐量较低（r = -0.40）以及血清甘油三酯较低（r = -0.63）相关。只有高强度活动与男性（r = -0.46）和女性（r = -0.41）的腰围呈负相关。女性报告的休闲活动水平与任何其他风险因素均无显著关联。低水平的体力活动与低高密度脂蛋白胆固醇（HDL - C）患病率相关，但报告的LTPA水平与两性血清HDL - C或血压的有利变化均无显著关联。
我们提供的证据表明，进行体力活动的亚洲印度人具有更有利的代谢综合征风险因素特征。结果突出表明需要鼓励亚洲印度移民，特别是女性进行体力活动，以降低代谢综合征的患病率。
