在日本人中，循环瘦素水平与身体活动或身体健康状况相关。
Circulating leptin levels are associated with physical activity or physical fitness in Japanese.
作者信息
Miyatake Nobuyuki, Murakami Haruka, Kawakami Ryoko, Tabata Izumi, Miyachi Motohiko
机构信息
Department of Hygiene, Faculty of Medicine, Kagawa University, Miki, Kagawa, 761-0793, Japan,
出版信息
Environ Health Prev Med. 2014 Sep;19(5):362-6. doi: 10.1007/s12199-014-0398-2. Epub 2014 Jul 22.
OBJECTIVE
The aim of this study was to evaluate the link between circulating leptin levels and physical activity and/or physical fitness in apparently healthy Japanese.
METHODS
A total of 85 men and 111 women who were not taking any medication were enrolled in this cross-sectional study. Circulating leptin levels, physical activity measured by tri-axial accelerometers and peak oxygen uptake were evaluated. We also assessed anthropometric data, blood pressure, blood examinations and energy intake.
RESULTS
Circulating leptin levels were 3.2 ± 2.3 ng/mL in men and 5.9 ± 3.8 ng/mL in women. Circulating leptin levels were significantly and positively correlated with body weight, body mass index, abdominal circumference, insulin and the homeostasis model assessment index, and significantly and negatively correlated with peak oxygen uptake in both sexes. Stepwise multiple regression showed that peak oxygen uptake in men and physical activity evaluated by Σ[metabolic equivalents h per week(METs h/w)]. in women were determinant factors for circulating leptin levels after adjusting for confounding factors.
目的
本研究旨在评估健康日本人群中循环瘦素水平与身体活动及/或身体素质之间的联系。
方法
本横断面研究共纳入85名男性和111名未服用任何药物的女性。评估循环瘦素水平、通过三轴加速度计测量的身体活动以及峰值摄氧量。我们还评估了人体测量数据、血压、血液检查和能量摄入。
结果
男性循环瘦素水平为3.2±2.3 ng/mL，女性为5.9±3.8 ng/mL。循环瘦素水平与体重、体重指数、腹围、胰岛素及稳态模型评估指数呈显著正相关，与男女两性的峰值摄氧量均呈显著负相关。逐步多元回归分析显示，在调整混杂因素后，男性的峰值摄氧量和女性通过每周代谢当量小时数（METs h/w）评估的身体活动是循环瘦素水平的决定因素。
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