Golfam Farzaneh, Golfam Parisa, Neghabi Zeinab
Mostafa Khomeini Hospital, Department of Surgery, Shahed University, Tehran, IR Iran.
Imam Reza Hospitah, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
Iran Red Crescent Med J. 2013 Jun;15(6):473-6. doi: 10.5812/ircmj.4026. Epub 2013 Jun 5.
Colorectal cancer (CRC) is one of the most common cancers worldwide which is not extensively researched in Iran.
The present study aims to investigate the epidemiologic characteristics of CRC in patients referred to selected hospitals of Tehran University of Medical Sciences.
In this descriptive-analytic study 218 patients with colorectal cancer were investigated. Data were collected via reviewing recorded pathologic results of patients of these hospitals which then were analyzed by univariant methods.
Among 218 patients, 140 (64.2%) were male and 78 (35.8%) were female. Of all patients, 132 (60.0%) suffered from tumors in rectum; 38 (17.4%) in sigmoid; 12 (5.5%) in descending colon; 10 (4.6%) in transverse colon and 26 (11.9%) in ascending colon and cecum. Tumors were well differentiated in 134 patients (61.5%), moderately in 62 cases (28.4%) and poorly differentiated in 22 patients (10.1%). There was no significant difference between males and females regarding the location and degree of tumor differentiation.
Regarding high prevalence of colorectal cancer in Iran and potential environmental and genetic factors, surveillance must be considered for this disease. Its risk factors such as diet, life style and low physical activity should be evaluated and screening should start at younger ages.
结直肠癌(CRC)是全球最常见的癌症之一,在伊朗尚未得到广泛研究。
本研究旨在调查转诊至德黑兰医科大学选定医院的结直肠癌患者的流行病学特征。
在这项描述性分析研究中,对218例结直肠癌患者进行了调查。通过查阅这些医院患者的病理记录结果收集数据,然后采用单变量方法进行分析。
在218例患者中,140例(64.2%)为男性,78例(35.8%)为女性。在所有患者中,132例(60.0%)患有直肠肿瘤;38例(17.4%)患有乙状结肠肿瘤;12例(5.5%)患有降结肠肿瘤;10例(4.6%)患有横结肠肿瘤;26例(11.9%)患有升结肠和盲肠肿瘤。134例患者(61.5%)的肿瘤分化良好,62例(28.4%)为中度分化,22例患者(10.1%)为低分化。在肿瘤位置和分化程度方面,男性和女性之间无显著差异。
鉴于伊朗结直肠癌的高患病率以及潜在的环境和遗传因素,必须对该疾病进行监测。应评估其饮食、生活方式和低体力活动等危险因素,并应在较年轻的年龄开始筛查。