Gupta Sanjeev, Bansal Radhika, Gupta Sunita, Jindal Nidhi, Jindal Abhinav
Department of Dermatology, MM Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India.
Department of Medicine, MM Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India.
Indian Dermatol Online J. 2013 Oct;4(4):267-72. doi: 10.4103/2229-5178.120635.
One billionth) is a novel arena with promising applications in the field of medicine, especially pharmaceuticals for safe and targeted drug delivery. The skin is a phenomenal tool for investigation of nanocarriers for drug delivery for topical and dermatological application. The physicochemical characteristics of the nanoparticles, such as rigidity, hydrophobicity, size and charge are crucial to the skin permeation mechanism. Many nanocarriers such as polymeric, inorganic and lipid nanoparticles and nanoemulsions have been developed and some like carbon nanotubes and fullerenes still need further exploration for future use in skin care and dermatological treatments. Risks of nanopollution and cytotoxicity also need to be kept in mind while exploring various nanoparticles for medical use.
纳米技术(十亿分之一)是一个具有新颖应用前景的领域,尤其在医学领域,特别是在安全和靶向给药的药物制剂方面。皮肤是研究用于局部和皮肤科应用的药物递送纳米载体的一个非凡工具。纳米颗粒的物理化学特性,如硬度、疏水性、大小和电荷,对皮肤渗透机制至关重要。已经开发了许多纳米载体,如聚合物、无机和脂质纳米颗粒以及纳米乳液,而一些纳米载体,如碳纳米管和富勒烯,在皮肤护理和皮肤科治疗中的未来应用仍需进一步探索。在探索各种纳米颗粒用于医疗用途时,也需要牢记纳米污染和细胞毒性的风险。