Nanomaterials have revolutionized various biological applications, including cosmeceuticals, enabling the development of smart nanocarriers for enhanced skin delivery. This review focuses on the role of nanotechnologies in skincare and treatments, providing a concise overview of smart nanocarriers, including thermo-, pH-, and multi-stimuli-sensitive systems, focusing on their design, fabrication, and applications in cosmeceuticals. These nanocarriers offer controlled release of active ingredients, addressing challenges like poor skin penetration and ingredient instability. This work discusses the unique properties and advantages of various nanocarrier types, highlighting their potential in addressing diverse skin concerns. Furthermore, we address the critical aspect of biocompatibility, examining potential health risks associated with nanomaterials. Finally, this review highlights current challenges, including the precise control of drug release, scalability, and the transition from in vitro to in vivo applications. We also discuss future perspectives such as the integration of digital technologies and artificial intelligence for personalized skincare to further advance the technology of smart nanocarriers in cosmeceuticals.