Diabetes Centre, Vaiola Hospital, Nuku'alofa, Kingdom of Tonga.
Diabetes Centre, Vaiola Hospital, Nuku'alofa, Kingdom of Tonga.
Obes Res Clin Pract. 2007 Jan;1(1):1-78. doi: 10.1016/j.orcp.2006.08.001.
There is growing concern that a single standard definition of overweight and obesity may not suit all ethnic groups. This study aimed to evaluate different anthropometric cut-points as indicators of risk for Type 2 diabetes (T2DM), hypertension and dyslipidaemia in a cross sectional, representative sample of the population of the Kingdom of Tonga (767 subjects: 314 males, 453 females). Anthropometric measurements included weight, height, waist circumference (WAIST), waist-to-hip ratio (WHR), weight-to-height ratio (WhgtR) and percentage body fat (%fat) using bioelectrical impedance. Risk factors investigated were systolic (sBP) and diastolic blood pressure (dBP), plasma glucose, total cholesterol, HDL cholesterol and triglycerides, hypertension and T2DM. The best predictive cut-points were identified using receiver operating characteristic (ROC) curves. The cut-points identified in this cross-sectional study contrast with those from studies in Caucasian and Asian populations. Optimal cut-points for predicting risk for T2DM, dyslipidaemia and hypertension in men were 29.3-31.7 kg/m(2) for BMI; 98.8-102.9 cm for WAIST; 0.91-0.93 for WHR and 0.56-0.60 for WhgtR. For women, the cut-points were 34.0-35.0 kg/m(2) (BMI), 100.0-102.8 cm (WAIST), 0.83-0.86 (WHR) and 0.60-0.62 (WhgtR). Mean area under the curve (AUC) measurements for each index ranged between 0.57 and 0.75 for men and 0.49 and 0.72 for women. The indexes with the highest AUCs for men were WAIST, WhgtR and BMI; and for women were WAIST and WhgtR. Use of a 100 cm tape for measuring WAIST is recommended as a simple public health and clinical indicator of risk until longitudinal follow-up studies can confirm findings of this study.:
人们越来越担心,超重和肥胖的单一标准定义可能并不适合所有种族群体。本研究旨在评估不同的人体测量学切点作为 2 型糖尿病(T2DM)、高血压和血脂异常风险的指标,研究对象为汤加王国的代表性横断面人群样本(767 人:314 名男性,453 名女性)。人体测量学测量包括体重、身高、腰围(WAIST)、腰臀比(WHR)、体重身高比(WhgtR)和使用生物电阻抗的体脂肪百分比(%fat)。研究的危险因素包括收缩压(sBP)和舒张压(dBP)、血浆葡萄糖、总胆固醇、高密度脂蛋白胆固醇和甘油三酯、高血压和 T2DM。使用受试者工作特征(ROC)曲线确定最佳预测切点。本横断面研究中确定的切点与白种人和亚洲人群研究中的切点形成对比。男性预测 T2DM、血脂异常和高血压风险的最佳切点为 BMI 为 29.3-31.7kg/m2;WAIST 为 98.8-102.9cm;WHR 为 0.91-0.93;WhgtR 为 0.56-0.60。对于女性,切点为 BMI 为 34.0-35.0kg/m2;WAIST 为 100.0-102.8cm;WHR 为 0.83-0.86;WhgtR 为 0.60-0.62。每个指数的平均曲线下面积(AUC)测量值范围为男性 0.57-0.75,女性 0.49-0.72。男性 AUC 最高的指数是 WAIST、WhgtR 和 BMI;女性是 WAIST 和 WhgtR。建议使用 100cm 卷尺测量 WAIST,作为简单的公共卫生和临床风险指标,直到纵向随访研究能够证实本研究的结果。