Hillesheim Elaine, Lima Luiz R A, Silva Rosane C R, Trindade Erasmo B S M
Department of Nutrition, Federal University of Santa Catarina, Florianópolis, Brazil.
Int J STD AIDS. 2014 May;25(6):439-47. doi: 10.1177/0956462413512808. Epub 2013 Dec 18.
This cross-sectional study aimed to investigate the nutritional status and dietary intake of HIV-infected children and adolescents and the relationship between nutritional status and dietary intake and CD4(+) T-cell count and viral load. The sample was composed of 49 subjects aged 7-17 years and living in Florianópolis, Brazil. Nutritional status was assessed by height-for-age and body mass index-for-age. Dietary intake was assessed by a food frequency questionnaire. Spearman correlations and multiple linear regressions were used to determine the relationship between energy, nutrient intake and body mass index-for-age and CD4(+) T-cell count and viral load. The mean body mass index-for-age and height-for-age values were -0.26 ± 0.86 and -0.56 ± 0.92, respectively. The energy intake was 50.8% above the estimated energy requirement and inadequate intake of polyunsaturated fat, cholesterol, fibre, calcium and vitamin C was present in 100%, 57.1%, 40.8%, 61.2% and 26.5% of the sample, respectively. Multiple linear regression analyses revealed that energy intake was correlated with CD4+ T-cell count (r = 0.33; p = 0.028) and viral load (r = -0.35; p = 0.019). These data showed low body mass index-for-age and height-for-age z-scores, high energy intake and inadequate intake of important nutrients for immune function, growth and control of chronic diseases. A lower energy intake was correlated with viral suppression and immune preservation.
这项横断面研究旨在调查感染艾滋病毒的儿童和青少年的营养状况和饮食摄入量，以及营养状况与饮食摄入量、CD4(+)T细胞计数和病毒载量之间的关系。样本由49名年龄在7至17岁、居住在巴西弗洛里亚诺波利斯的受试者组成。通过年龄别身高和年龄别体重指数评估营养状况。通过食物频率问卷评估饮食摄入量。使用Spearman相关性分析和多元线性回归分析来确定能量、营养素摄入量与年龄别体重指数、CD4(+)T细胞计数和病毒载量之间的关系。年龄别体重指数和年龄别身高值的平均值分别为-0.26±0.86和-0.56±0.92。能量摄入量比估计能量需求高50.8%，样本中100%、57.1%、40.8%、61.2%和26.5%的人分别存在多不饱和脂肪、胆固醇、纤维、钙和维生素C摄入不足的情况。多元线性回归分析显示，能量摄入量与CD4+T细胞计数(r = 0.33; p = 0.028)和病毒载量(r = -0.35; p = 0.019)相关。这些数据表明年龄别体重指数和年龄别身高的z评分较低，能量摄入量高，免疫功能、生长和慢性病控制所需的重要营养素摄入不足。较低的能量摄入量与病毒抑制和免疫保护相关。
