Gudowska I, Ardenfors O, Toma-Dasu I, Dasu A
Medical Radiation Physics, Department of Physics, Stockholm University, Box 260, Stockholm 171 76, Sweden
Medical Radiation Physics, Department of Physics, Stockholm University, Box 260, Stockholm 171 76, Sweden Department of Medical Physics, Karolinska University Hospital, Stockholm 171 76, Sweden.
Radiat Prot Dosimetry. 2014 Oct;161(1-4):357-62. doi: 10.1093/rpd/nct335. Epub 2013 Dec 18.
Ionising radiation is increasingly used for the treatment of cancer, being the source of a considerable fraction of the medical irradiation to patients. With the increasing success rate of cancer treatments and longer life expectancy of the treated patients, the issue of secondary cancer incidence is of growing concern, especially for paediatric patients who may live long after the treatment and be more susceptible to carcinogenesis. Also, additional imaging procedures like computed tomography, kilovoltage and megavoltage imaging and positron emission tomography, alone or in conjunction with radiation therapy, may add to the radiation burden associated with the risk of occurrence of secondary cancers. This work has been based on literature studies and is focussed on the assessment of secondary doses to healthy tissues that are delivered by the use of modern radiation therapy and diagnostic imaging modalities in the clinical environment.
电离辐射越来越多地用于癌症治疗，是患者接受的医学照射中相当一部分的来源。随着癌症治疗成功率的提高以及接受治疗患者的预期寿命延长，继发性癌症发病率问题日益受到关注，尤其是对于那些在治疗后可能长期存活且更易发生癌变的儿科患者。此外，诸如计算机断层扫描、千伏和兆伏成像以及正电子发射断层扫描等额外的成像程序，单独使用或与放射治疗联合使用，可能会增加与继发性癌症发生风险相关的辐射负担。这项工作基于文献研究，重点是评估在临床环境中使用现代放射治疗和诊断成像方式时对健康组织的继发性剂量。
