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甲状旁腺激素与体育锻炼:简要综述

Parathyroid hormone and physical exercise: a brief review.

作者信息

Bouassida Anissa, Latiri Imed, Bouassida Semi, Zalleg Dalenda, Zaouali Monia, Feki Youssef, Gharbi Najoua, Zbidi Abdelkarim, Tabka Zouhair

机构信息

Laboratory of Cardio-Circulatory, Respiratory, Metabolic and Hormonal Adaptations to the Muscular Exercise , Faculty of Medicine Ibn El Jazzar, 4002 Sousse, Tunisia.

Laboratory of Physiology, ISSEP Ksar-Saîd , Tunis, Tunisia.

出版信息

J Sports Sci Med. 2006 Sep 1;5(3):367-74.

Abstract

Parathyroid hormone (PTH) is the major hormone regulating calcium metabolism and is involved in both catabolic and anabolic actions on bone. Intermittent PTH exposure can stimulate bone formation and bone mass when PTH has been injected. In contrast, continuous infusion of PTH stimulates bone resorption. PTH concentration may be affected by physical exercise and our review was designed to investigate this relationship. The variation in PTH concentration appears to be influenced by both exercise duration and intensity. There probably exists a stimulation threshold of exercise to alter PTH. PTH regulation is also influenced by the initial bone mineral content, age, gender, training state, and other hormonal and metabolic factors (catecholamines, lactic acid and calcium concentrations). Key PointsPhysical exercise can improve PTH secretion.PARATHYROID HORMONE HAS BOTH ANABOLIC AND CATABOLIC EFFECTS ON BONE: intermittent treatment of PTH is anabolic whereas continuous treatment is catabolic.

摘要

甲状旁腺激素(PTH)是调节钙代谢的主要激素,参与对骨骼的分解代谢和合成代谢作用。当注射PTH时,间歇性暴露于PTH可刺激骨形成和骨量增加。相反,持续输注PTH会刺激骨吸收。PTH浓度可能受体育锻炼的影响,我们的综述旨在研究这种关系。PTH浓度的变化似乎受运动持续时间和强度的影响。可能存在改变PTH的运动刺激阈值。PTH的调节还受初始骨矿物质含量、年龄、性别、训练状态以及其他激素和代谢因素(儿茶酚胺、乳酸和钙浓度)的影响。要点体育锻炼可改善PTH分泌。甲状旁腺激素对骨骼具有合成代谢和分解代谢作用:间歇性PTH治疗具有合成代谢作用,而持续治疗具有分解代谢作用。

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