Ulfarsson Trandur, Lundgren-Nilsson Asa, Blomstrand Christian, Nilsson Michael
Center for Brain Repair and Rehabilitation (CBR), Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg , Gothenburg , Sweden .
Brain Inj. 2014;28(3):328-35. doi: 10.3109/02699052.2013.865274. Epub 2013 Dec 19.
The consequences of pre-morbid factors in adults with severe traumatic brain injury have not been widely addressed. This study aimed to determine whether being unemployed or on sick leave before injury influences long-term health-related quality-of-life (HRQoL) and functioning in patients with severe traumatic brain injury.
Fifty-one consecutive patients were studied; aged 16-65 years, with severe traumatic brain injury who were admitted to Sahlgrenska University Hospital, Gothenburg, from 1999-2002.
The patients were assessed once, 2-11 years after trauma. Data from the time of injury were combined into a validated prognostic model to adjust for injury severity. Data on sick leave and unemployment before injury were gathered from the Swedish social insurance agency. Outcomes were measured with the Short Form-36 Health Survey, the Glasgow Outcome Scale-Extended, and a self-report questionnaire specifically designed for this study to measure functioning.
In a multivariate analysis, a history of sick leave/unemployment predicted a worse long-term global outcome, more problems with personal activities of daily living and worse HRQoL.
These results should be considered when refining outcome predictions and optimizing rehabilitation interventions for patients with severe traumatic brain injury.
病前因素对重度创伤性脑损伤成年患者的影响尚未得到广泛研究。本研究旨在确定受伤前处于失业状态或休病假是否会影响重度创伤性脑损伤患者的长期健康相关生活质量(HRQoL)和功能。
对连续51例患者进行了研究;年龄在16 - 65岁之间,患有重度创伤性脑损伤,于1999年至2002年入住哥德堡萨尔格伦斯卡大学医院。
在创伤后2 - 11年对患者进行一次评估。将受伤时的数据纳入一个经过验证的预后模型,以调整损伤严重程度。受伤前病假和失业的数据来自瑞典社会保险机构。使用简短健康调查问卷36项、扩展格拉斯哥预后量表以及专门为本研究设计的自我报告问卷来测量功能,以此评估结果。
在多变量分析中,病假/失业史预示着长期总体预后较差、日常生活个人活动方面问题更多以及健康相关生活质量更差。
在完善重度创伤性脑损伤患者的预后预测和优化康复干预措施时,应考虑这些结果。