Forslund Marit V, Perrin Paul B, Sigurdardottir Solrun, Howe Emilie I, van Walsem Marleen R, Arango-Lasprilla Juan Carlos, Lu Juan, Aza Alba, Jerstad Tone, Røe Cecilie, Andelic Nada
Department of Physical Medicine and Rehabilitation, Oslo University Hospital, 0424 Oslo, Norway.
Departments of Psychology and Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA 23233, USA.
J Clin Med. 2021 Jan 5;10(1):157. doi: 10.3390/jcm10010157.
Traumatic brain injury (TBI) has a long-lasting impact on participation and health-related quality of life (HRQL). We aimed to describe the physical and mental health trajectories and to identify their predictors across the first 10 years after TBI. A prospective longitudinal cohort of 97 individuals with moderate to severe TBI (age 16-55 years) in Norway were followed up at 1, 2, 5, and 10 years post-injury. Their socio-demographic and injury characteristics were recorded at baseline; their responses to the 36-Item Short Form Health Survey (SF-36) were collected at each follow-up. The Physical (PCS) and Mental Component Summary (MCS) scores were used as the outcome measures of physical and mental health. The predictors of the trajectories were described and examined using hierarchical linear modelling. The subscale scores showed a stable or increasing trend, but only the Role Physical and Role Emotional subscales showed clinically relevant positive changes from 1 to 10 years post-injury. Longer time, male gender, employment pre-injury, and shorter length of post-traumatic amnesia were significant predictors of better physical health trajectories; longer time, male gender, and employment pre-injury were significant predictors of better mental health trajectories. At-risk individuals may be targeted to receive rehabilitation interventions to improve their long-term quality of life outcomes.
创伤性脑损伤（TBI）对参与度和健康相关生活质量（HRQL）具有长期影响。我们旨在描述身心健康轨迹，并确定创伤性脑损伤后首个10年内这些轨迹的预测因素。在挪威，对97名中度至重度创伤性脑损伤患者（年龄在16 - 55岁之间）进行了前瞻性纵向队列研究，在受伤后1年、2年、5年和10年进行随访。在基线时记录他们的社会人口统计学和损伤特征；在每次随访时收集他们对36项简短健康调查问卷（SF - 36）的回答。身体成分总结（PCS）分数和心理成分总结（MCS）分数用作身心健康的结果指标。使用分层线性模型描述并检验轨迹的预测因素。分量表分数显示出稳定或上升趋势，但只有身体功能和情感角色分量表在受伤后1至10年显示出具有临床意义的积极变化。更长的时间、男性性别、受伤前就业以及创伤后遗忘期较短是身体健康轨迹较好的显著预测因素；更长的时间、男性性别和受伤前就业是心理健康轨迹较好的显著预测因素。有风险的个体可能需要接受康复干预，以改善他们的长期生活质量结果。
