ENT Department, University Hospital of Ferrara, Ferrara, Italy.
Int J Immunopathol Pharmacol. 2013 Oct-Dec;26(4):965-71. doi: 10.1177/039463201302600416.
Fine-needle aspiration cytology (FNAC) is a minimally invasive procedure usually well tolerated, easy to perform, quick, cheap and easy to repeat in case of doubts or non-diagnostic results. Echography is also a fast, cheap and non-invasive tool; however, the role of FNAC and echography in the diagnosis of salivary gland pathology is not universally recognised. Three hundred and fifty-seven patients with a cytological diagnosis at FNAC, and 247 of these who were also studied with echography, were enrolled for this retrospective study. The final histopathological diagnoses, obtained after surgery, were then compared to the preoperative FNAC diagnoses and echographic findings. From the analysis of our data, the overall FNAC specificity resulted 93 percent, sensitivity 83 percent, and diagnostic accuracy 92 percent. Echography sensibility was 57.1 percent specificity 98.2 percent, while positive and negative predictive value were respectively 80 percent and 94.8 percent. While echography can be useful in order to provide a better characterization of salivary gland lesions, FNAC can then be considered a safe diagnostic tool with reliable sensitivity and specificity for the assessment of salivary gland pathology and thus for selecting patients and indicating the best surgical treatment.
细针吸取细胞学（FNAC）是一种微创程序，通常耐受性良好，易于操作，快速，廉价，并且在有疑问或诊断结果不理想时易于重复。超声检查也是一种快速、廉价和非侵入性的工具；然而，FNAC 和超声检查在唾液腺病理学诊断中的作用并未得到普遍认可。本回顾性研究纳入了 357 名接受 FNAC 细胞学诊断的患者，其中 247 名患者还接受了超声检查。随后将手术获得的最终组织病理学诊断与术前 FNAC 诊断和超声检查结果进行比较。从我们的数据分析中，FNAC 的总体特异性为 93%，敏感性为 83%，诊断准确性为 92%。超声检查的敏感性为 57.1%，特异性为 98.2%，阳性和阴性预测值分别为 80%和 94.8%。虽然超声检查有助于更好地描述唾液腺病变，但 FNAC 可以被认为是一种安全的诊断工具，具有可靠的敏感性和特异性，可用于评估唾液腺病理学，从而选择患者并指示最佳手术治疗。
