Department of Cytopathology, Alpha Prolipsis Medical Laboratories, 163 Mesogion Street, 11526, Athens, Greece.
Head Neck Pathol. 2021 Sep;15(3):780-786. doi: 10.1007/s12105-020-01278-1. Epub 2021 Jan 18.
This study aimed to present the 2-year experience of the implementation of the Milan System for Reporting Salivary Gland Cytopathology at Alpha Prolipsis Medical Laboratories, a private medical laboratory located in Athens, Greece. A totaI of 102 Fine Needle Aspirations (FNAs) performed since 2018 were included in the study. Reports were issued according to the Milan System for Reporting Salivary Gland Cytopathology. Aspirates were prepared with both conventional and liquid-based cytological methods and were evaluated by two or three Board-certified cytopathologists. Diagnostic reproducibility and accuracy were evaluated. All cases included in this study had histologic follow-up. The diagnostic accuracy of FNA for differentiating between benign and malignant disease according to MSRSGC classification was 93.3%, the specificity was 97.5% and the sensitivity was 82.2%. The positive and negative predictive values were 93.2 and 87.2%, respectively. Our results show that FNA is a valuable examination technique in the preoperative evaluation of salivary gland lesions. The integration of the 2018 Milan System for Reporting Salivary Gland Cytopathology is effective, with an overall accuracy around 95%.
本研究旨在展示米兰系统在 Alpha Prolipsis 医学实验室（一家位于希腊雅典的私人医学实验室）报告唾液腺细胞学方面的实施经验，该实验室自 2018 年以来共进行了 102 例细针抽吸（FNA）。报告根据米兰系统报告唾液腺细胞学进行发布。抽吸物采用常规和液基细胞学方法制备，并由两名或三名经过董事会认证的细胞病理学家进行评估。评估了诊断的可重复性和准确性。本研究中包括的所有病例均有组织学随访。根据 MSRSGC 分类，FNA 对区分良性和恶性疾病的诊断准确性为 93.3%，特异性为 97.5%，敏感性为 82.2%。阳性和阴性预测值分别为 93.2%和 87.2%。我们的结果表明，FNA 是唾液腺病变术前评估的一种有价值的检查技术。2018 年米兰系统报告唾液腺细胞学的整合是有效的，总体准确性约为 95%。
