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抗生素耐药性急性甲沟炎的临床和细胞学特征。

Clinical and cytologic features of antibiotic-resistant acute paronychia.

机构信息

Başkent University Faculty of Medicine, Department of Dermatology, Adana Hospital, Adana, Turkey.

Department of Dermatology, Second University of Naples, Naples, Italy.

出版信息

J Am Acad Dermatol. 2014 Jan;70(1):120-6.e1. doi: 10.1016/j.jaad.2013.09.042.

DOI:10.1016/j.jaad.2013.09.042
PMID:24355264
Abstract

BACKGROUND

Acute paronychia usually is treated as a bacterial infection, but antibiotic-resistant acute paronychia may be caused by other infectious and noninfectious problems.

OBJECTIVE

We sought to describe the clinical, etiologic, cytologic, and therapeutic features of antibiotic-resistant acute paronychia.

METHODS

A retrospective review of medical records and cytology was performed in 58 patients (age, 1 month-91 years; 36 children and adolescents [62%] and 22 adults [38%]) who had antibiotic-resistant acute paronychias.

RESULTS

Causes of paronychia included bacteria (25 patients [43%]), viruses (21 patients [36%]), fungi (5 patients [9%]), drugs (3 patients [5%]), pemphigus vulgaris (3 patients [5%]), and trauma (1 patient [2%]). Diagnostic cytologic findings were noted in 54 patients (93%); no diagnostic cytologic findings were present with drug-induced (3 patients) or traumatic (1 patient) paronychia. The most common predisposing factors were the habits of finger- or thumb-sucking (14 patients [24%]) and nail-biting (11 patients [19%]). Complications included id reaction with erythema multiforme in 3 patients (5%).

LIMITATIONS

Limitations include retrospective study design from 1 treatment center.

CONCLUSION

Antibiotic-resistant acute paronychia may be infectious or noninfectious. Cytologic examination with Tzanck smear may be useful diagnostically and may prevent unnecessary use of antibiotics and surgical drainage.

摘要

背景

急性甲沟炎通常被视为细菌感染,但抗生素耐药性急性甲沟炎可能由其他传染性和非传染性问题引起。

目的

我们旨在描述抗生素耐药性急性甲沟炎的临床、病因、细胞学和治疗特征。

方法

对 58 例(年龄 1 个月至 91 岁;36 例儿童和青少年[62%]和 22 例成年人[38%])抗生素耐药性急性甲沟炎患者的病历和细胞学进行回顾性研究。

结果

甲沟炎的病因包括细菌(25 例[43%])、病毒(21 例[36%])、真菌(5 例[9%])、药物(3 例[5%])、寻常性天疱疮(3 例[5%])和创伤(1 例[2%])。54 例(93%)患者有诊断性细胞学发现;药物诱导(3 例)或创伤性(1 例)甲沟炎无诊断性细胞学发现。最常见的诱发因素是吮指(14 例[24%])和咬甲(11 例[19%])习惯。并发症包括 3 例(5%)患者出现红斑多形性反应。

局限性

局限性包括来自 1 个治疗中心的回顾性研究设计。

结论

抗生素耐药性急性甲沟炎可能是传染性或非传染性的。Tzanck 涂片细胞学检查在诊断上可能有用,并可防止不必要地使用抗生素和外科引流。

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