Schicho Rudolf, Storr Martin
Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Pharmacology. 2014;93(1-2):1-3. doi: 10.1159/000356512. Epub 2013 Dec 17.
In ancient medicine, cannabis has been widely used to cure disturbances and inflammation of the bowel. A recent clinical study now shows that the medicinal plant Cannabis sativa has lived up to expectations and proved to be highly efficient in cases of inflammatory bowel diseases. In a prospective placebo-controlled study, it has been shown what has been largely anticipated from anecdotal reports, i.e. that cannabis produces significant clinical benefits in patients with Crohn's disease. The mechanisms involved are not yet clear but most likely include peripheral actions on cannabinoid receptors 1 and 2, and may also include central actions.
在古代医学中，大麻就已被广泛用于治疗肠道紊乱和炎症。最近一项临床研究表明，药用植物大麻已不负众望，在治疗炎症性肠病方面被证明具有很高的疗效。在一项前瞻性安慰剂对照研究中，已证实了从轶事报道中大致预期的结果，即大麻对克罗恩病患者具有显著的临床益处。其中涉及的机制尚不清楚，但很可能包括对大麻素受体1和2的外周作用，也可能包括中枢作用。
