Merck Stiftungsprofessur für Molekulare Biotechnologie, Fachbereich Biowissenschaften, Goethe Universität Frankfurt, Max-von-Laue-Str. 9, Biozentrum/Campus Riedberg, 60438 Frankfurt am Main, Germany.
Nat Prod Rep. 2014 Jan 17;31(2):154-9. doi: 10.1039/c3np70081j.
Highlight describes the recently discovered prodrug activation mechanism found in the biosynthesis of nonribosomally produced peptides and peptide/polyketide hybrids as well as related mechanisms.
高亮描述了非核糖体合成的肽和肽/聚酮杂合化合物生物合成中发现的最近被揭示的前药激活机制,以及相关的机制。