Darcey J, Devlin H, Lai D, Walsh T, Southern H, Marjanovic E, Horner K
Speciality Registrar and Honorary Lecturer in Restorative Dentistry, University of Manchester.
Professor in Restorative Dentistry, University of Manchester.
Br Dent J. 2013 Dec;215(12):617-621. doi: 10.1038/sj.bdj.2013.1191.
There is evidence to suggest osteoporosis may result in premature tooth loss. The pathology behind this relationship is poorly understood. A correlation with osteoporosis and greater susceptibility to periodontal disease has been suggested.
To investigate the association between osteoporosis and periodontal disease, accounting for the effect of confounding variables of age, smoking status and oral hygiene.Setting Three hundred and fifty-nine postmenopausal women aged 45-70 years were recruited from the Greater Manchester area between March 2008 and June 2010.Subjects and methods Data were collected on osteoporosis status, smoking status, pocket probing depths, suppuration, plaque, bleeding and calculus indices. Dental panoramic tomographs were taken and periodontal bone support assessed on all teeth. Data were analysed using SPSS software (version 20).
Complete data were available for 348 patients. Twenty-six percent (91) of individuals were osteoporotic. Logistic regression was used. The relationship between osteoporosis status and moderate to severe periodontal disease of both molar teeth and the whole mouth was not significant (p = 0.088 and p = 0.296 respectively).
Osteoporosis is not a causal factor in the development of moderate to severe chronic periodontitis.
有证据表明骨质疏松症可能导致牙齿过早脱落。这种关系背后的病理机制尚不清楚。有人提出骨质疏松症与牙周病易感性增加之间存在关联。
研究骨质疏松症与牙周病之间的关联，同时考虑年龄、吸烟状况和口腔卫生等混杂变量的影响。
2008年3月至2010年6月期间，从大曼彻斯特地区招募了359名年龄在45 - 70岁之间的绝经后女性。
收集了有关骨质疏松症状况、吸烟状况、牙周袋探诊深度、化脓情况、牙菌斑、出血和牙石指数的数据。拍摄牙科全景断层扫描片，并评估所有牙齿的牙周骨支持情况。使用SPSS软件（版本20）进行数据分析。
348名患者有完整数据。26%（91名）个体患有骨质疏松症。采用逻辑回归分析。骨质疏松症状况与磨牙及全口中度至重度牙周病之间的关系不显著（分别为p = 0.088和p = 0.296）。
骨质疏松症不是中度至重度慢性牙周炎发生的因果因素。
