Department of Health Science, University of Milan Bicocca, Clinica Pneumologica, AO San Gerardo, Via Pergolesi 33, Monza, Italy; University of Texas Health Science Center at San Antonio, TX, USA.
Department of Health Science, University of Milan Bicocca, Clinica Pneumologica, AO San Gerardo, Via Pergolesi 33, Monza, Italy.
Eur J Intern Med. 2014 Apr;25(4):312-9. doi: 10.1016/j.ejim.2013.12.001. Epub 2013 Dec 17.
Pneumonia is one of the main causes of morbidity and mortality in the elderly. The elderly population has exponentially increased in the last decades and the current epidemiological trends indicate that it is expected to further increase. Therefore, recognizing the special needs of older people is of paramount importance. In this review we address the main differences between elderly and adult patients with pneumonia. We focus on several aspects, including the atypical clinical presentation of pneumonia in the elderly, the methods to assess severity of illness, the appropriate setting of care, and the management of comorbidities. We also discuss how to approach the common complications of severe pneumonia, including acute respiratory failure and severe sepsis. Moreover, we debate whether or not elderly patients are at higher risk of infection due to multi-drug resistant pathogens and which risk factors should be considered when choosing the antibiotic therapy. We highlight the differences in the definition of clinical stability and treatment failure between adults and elderly patients. Finally, we review the main outcomes, preventive and supportive measures to be considered in elderly patients with pneumonia.
肺炎是老年人发病率和死亡率的主要原因之一。在过去几十年中,老年人口呈指数级增长,目前的流行病学趋势表明,这一数字还将进一步增加。因此,认识到老年人的特殊需求至关重要。在这篇综述中,我们探讨了肺炎在老年患者和成年患者之间的主要差异。我们重点关注了几个方面,包括老年人肺炎不典型的临床表现、评估疾病严重程度的方法、适当的护理环境以及合并症的管理。我们还讨论了如何处理严重肺炎的常见并发症,包括急性呼吸衰竭和严重败血症。此外,我们还探讨了老年患者是否因耐多药病原体而面临更高的感染风险,以及在选择抗生素治疗时应考虑哪些危险因素。我们强调了成年人和老年患者之间在临床稳定和治疗失败定义上的差异。最后,我们综述了肺炎老年患者的主要结局、预防和支持措施。