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联合使用 BinaxNOW 葡萄球菌检测和 Clearview PBP2a 检测,从阳性血培养物中早期检测耐甲氧西林金黄色葡萄球菌。

Combined use of the BinaxNOW Staphylococcus aureus test with the Clearview PBP2a assay for the early detection of methicillin-resistant S. aureus from positive blood cultures.

机构信息

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, PR China.

Center of Clinical Laboratory, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, PR China.

出版信息

Diagn Microbiol Infect Dis. 2014 Mar;78(3):226-8. doi: 10.1016/j.diagmicrobio.2013.11.018. Epub 2013 Nov 27.

Abstract

The use of combination 2 novel immunochromatographic assays for same-day detection of methicillin-resistant Staphylococcus aureus (MRSA) from positive blood cultures was evaluated. Compared to the standard culture methods, the BinaxNOW® S. aureus test demonstrated 98.7% sensitivity and 100% specificity in correctly identifying S. aureus. The sensitivity and specificity of the Clearview® PBP2a assay in differentiating MRSA from methicillin-susceptible S. aureus were 97.1% and 100%.

摘要

评估了两种新型免疫层析检测法联合应用于同日检测阳性血培养物中耐甲氧西林金黄色葡萄球菌(MRSA)的效果。与标准培养方法相比,BinaxNOW®金黄色葡萄球菌检测法在正确鉴定金黄色葡萄球菌方面的灵敏度和特异性分别为 98.7%和 100%。Clearview®PBP2a 检测法在区分 MRSA 和甲氧西林敏感金黄色葡萄球菌方面的灵敏度和特异性分别为 97.1%和 100%。

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