神经元反弹放电、共振频率和θ周期跳跃可能有助于内嗅皮质中网格细胞的放电。
Neuronal rebound spiking, resonance frequency and theta cycle skipping may contribute to grid cell firing in medial entorhinal cortex.
作者信息
Hasselmo Michael E
机构信息
Center for Memory and Brain, Department of Psychology and Graduate Program for Neuroscience, Boston University, , 2 Cummington St., Boston, MA 02215, USA.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2013 Dec 23;369(1635):20120523. doi: 10.1098/rstb.2012.0523. Print 2014 Feb 5.
Abstract
Data show a relationship of cellular resonance and network oscillations in the entorhinal cortex to the spatial periodicity of grid cells. This paper presents a model that simulates the resonance and rebound spiking properties of entorhinal neurons to generate spatial periodicity dependent upon phasic input from medial septum. The model shows that a difference in spatial periodicity can result from a difference in neuronal resonance frequency that replicates data from several experiments. The model also demonstrates a functional role for the phenomenon of theta cycle skipping in the medial entorhinal cortex.
摘要
数据显示，内嗅皮层中的细胞共振和网络振荡与网格细胞的空间周期性存在关联。本文提出了一个模型，该模型模拟内嗅神经元的共振和反弹放电特性，以根据来自内侧隔区的相位输入生成空间周期性。该模型表明，空间周期性的差异可能源于神经元共振频率的差异，这与多个实验的数据相符。该模型还证明了内侧内嗅皮层中θ周期跳跃现象的功能作用。
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本文引用的文献
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