Roupakias Stylianos, Sinopidis Xenophon, Karatza Ageliki, Varvarigou Anastasia
Department of Pediatric Surgery, University of Patras Medical School, Patras, Greece
Department of Pediatric Surgery, University of Patras Medical School, Patras, Greece.
Clin Pediatr (Phila). 2014 Oct;53(12):1119-33. doi: 10.1177/0009922813515744. Epub 2013 Dec 23.
Approaches to the management of children with urinary tract infection (UTI), vesicoureteral reflux (VUR), and renal scars have been challenged and have become controversial over the past decade. It is difficult to determine when, how, and which patients will benefit from the diagnosis and management of this condition. Therefore, the issues of diagnostic imaging, observation, follow-up, and intervention tend to be decided more on a case-by-case basis, rather than by using an algorithm. Over the past few years, there have been advances in the identification of risk factors that predispose patients with UTI to present with VUR, to develop recurrent UTIs and renal scars, to have deteriorating renal function, to show VUR improvement and/or spontaneous resolution, and to be candidates for and benefit from early surgical intervention.
在过去十年中，针对患有尿路感染（UTI）、膀胱输尿管反流（VUR）和肾瘢痕的儿童的管理方法受到了挑战，并引发了争议。很难确定何时、如何以及哪些患者将从这种疾病的诊断和管理中受益。因此，诊断成像、观察、随访和干预等问题往往更多地根据具体情况来决定，而不是采用某种算法。在过去几年里，在识别风险因素方面取得了进展，这些风险因素使患有UTI的患者易出现VUR、发生复发性UTI和肾瘢痕、肾功能恶化、VUR改善和/或自发缓解，以及成为早期手术干预的候选者并从中受益。
