带蒂乳房缩小成形术治疗大乳房乳腺癌
Therapeutic reduction mammoplasty in large-breasted women with cancer using superior and superomedial pedicles.
机构信息
Surgical Oncology Department, Oncology Center, Mansoura, Egypt.
Clinical Oncology and Nuclear Medicine Department, Mansoura University, Mansoura, Egypt.
出版信息
Breast Cancer (Dove Med Press). 2012 Oct 25;4:167-72. doi: 10.2147/BCTT.S32766. eCollection 2012.
BACKGROUND
Surgical management of breast cancer in large-breasted women presents a real challenge. This study aims to evaluate the outcome of therapeutic reduction mammoplasty in large-breasted women with breast cancer using superior and superomedial pedicles, situated at any breast quadrant except for the central and upper medial quadrants.
METHODS
Fifty women with breast cancer and large breasts underwent simultaneous bilateral reduction mammoplasty. The weight of the tissue removed ranged from 550 g to 1050 g and the tumor-free safety margins by frozen section were in the range of 4 cm to 12 cm.
RESULTS
The age of the patients ranged from 36 to 58 (median 43) years and tumor size ranged from 1 cm to 4 cm. The cosmetic outcomes were excellent in 32 patients (64%), good in 15 (30%) patients, and fair in three patients (6%). The follow-up period was 8-36 (mean 20) months, with no local recurrence or systemic metastasis.
CONCLUSION
Therapeutic reduction mammoplasty using superior and superomedial pedicles was shown to be oncologically safer than traditional conservative surgery. This oncoplastic procedure yields a satisfactory esthetic outcome with lower morbidity in large-breasted women with breast cancer.
背景
大乳房女性的乳腺癌手术治疗具有一定挑战性。本研究旨在评估采用上方和内侧上方蒂的乳房缩小成形术治疗除中央和内侧上象限以外的任何乳房象限的大乳房乳腺癌患者的治疗效果。
方法
50 名患有乳腺癌且乳房较大的女性接受了双侧同期乳房缩小成形术。切除的组织重量范围为 550 克至 1050 克，冷冻切片的肿瘤无切缘安全范围为 4 厘米至 12 厘米。
结果
患者年龄为 36 至 58 岁（中位数 43 岁），肿瘤大小为 1 厘米至 4 厘米。32 例（64%）患者的美容效果为优秀，15 例（30%）患者为良好，3 例（6%）患者为一般。随访时间为 8-36 个月（平均 20 个月），无局部复发或全身转移。
结论
与传统的保守手术相比，采用上方和内侧上方蒂的乳房缩小成形术在肿瘤学上更安全。这种肿瘤整形手术可在大乳房乳腺癌患者中产生满意的美容效果，且发病率更低。
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