Njei Basile, Konjeti Venkata Rajesh, Sanchez Harold
Department of Medicine, University of Connecticut, Farmington, USA.
The Hospital of Central Connecticut, New Britain, USA.
Conn Med. 2013 Nov-Dec;77(10):591-4.
Klatskin tumors are the most common type of cholangiocarcinomas. They are perihilar tumors usually found at the bifurcation of right and left hepatic ducts. The absence of early symptoms leads to the diagnosis of most Klatskin tumors at an advanced incurable stage. Despite emerging adjuvant treatment regimens, survival outcomes remain poor. Surgery is currently the standard of care and the only curative treatment modality available. In this manuscript, we share our experience with an asymptomatic patient with elevated liver enzymes, who was found to have a Klatskin tumor, extending into the left hepatic duct. The patient's diagnosis, management, and prognosis are discussed. The case highlights the importance of screening for hepato-biliary malignancies in elderly patients with abnormal liver function markers.
肝门部肿瘤是胆管癌最常见的类型。它们是肝门周围肿瘤,通常位于左右肝管分叉处。早期症状的缺乏导致大多数肝门部肿瘤在晚期无法治愈阶段才被诊断出来。尽管出现了辅助治疗方案,但生存结果仍然很差。手术目前是标准的治疗方法,也是唯一可用的治愈性治疗方式。在本手稿中,我们分享了一位肝功能酶升高的无症状患者的经验,该患者被发现患有肝门部肿瘤,肿瘤延伸至左肝管。讨论了该患者的诊断、治疗和预后。该病例强调了对肝功能指标异常的老年患者进行肝胆恶性肿瘤筛查的重要性。