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Quality of life of people living with HIV and AIDS and antiretroviral therapy.感染艾滋病毒和艾滋病者的生活质量与抗逆转录病毒疗法
HIV AIDS (Auckl). 2012;4:117-24. doi: 10.2147/HIV.S32321. Epub 2012 Aug 6.
2
Factors influencing adherence to antiretroviral treatment in Nepal: a mixed-methods study.影响尼泊尔抗逆转录病毒治疗依从性的因素:一项混合方法研究。
PLoS One. 2012;7(5):e35547. doi: 10.1371/journal.pone.0035547. Epub 2012 May 1.
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Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice.尼日利亚抗逆转录病毒疗法的依从性:研究综述及其对政策与实践的启示
HIV AIDS (Auckl). 2010;2:69-76. doi: 10.2147/hiv.s9280. Epub 2010 Mar 30.
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Determinants of non-adherence to subsidized anti-retroviral treatment in southeast Nigeria.尼日利亚东南部对抗逆转录病毒补贴治疗不依从的决定因素
Health Policy Plan. 2009 May;24(3):189-96. doi: 10.1093/heapol/czp006. Epub 2009 Mar 10.
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Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model.将普遍自愿艾滋病毒检测与立即进行抗逆转录病毒治疗作为消除艾滋病毒传播的策略:一个数学模型
Lancet. 2009 Jan 3;373(9657):48-57. doi: 10.1016/S0140-6736(08)61697-9. Epub 2008 Nov 27.
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Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy.在一个开始接受三联抗逆转录病毒疗法的大型未接受过抗逆转录病毒治疗队列中,HIV耐药性突变的预测因素。
J Infect Dis. 2005 Feb 1;191(3):339-47. doi: 10.1086/427192. Epub 2004 Dec 22.
7
Adherence is not a barrier to successful antiretroviral therapy in South Africa.在南非,坚持治疗并非成功进行抗逆转录病毒治疗的障碍。
AIDS. 2003 Jun 13;17(9):1369-75. doi: 10.1097/00002030-200306130-00011.

尼日利亚纽维市纳姆迪·阿齐克韦大学教学医院接受抗逆转录病毒治疗的HIV感染成人的不依从因素及社会人口学特征

Nonadherence Factors and Sociodemographic Characteristics of HIV-Infected Adults Receiving Antiretroviral Therapy in Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

作者信息

Okoronkwo Ijeoma, Okeke Uchenna, Chinweuba Anthonia, Iheanacho Peace

机构信息

Department of Nursing Sciences, University of Nigeria, Enugu Campus, Enugu, Nigeria.

Department of Nursing Sciences, University of Nigeria, Enugu Campus, Enugu, Nigeria ; Nursing Services Department, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

出版信息

ISRN AIDS. 2013 Nov 28;2013:843794. doi: 10.1155/2013/843794. eCollection 2013.

DOI:10.1155/2013/843794
PMID:24369526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3863502/
Abstract

Adherence to treatment instructions with antiretroviral therapy (ART) is very crucial for successful treatment outcome. However, sticking to treatment instructions pose-great challenges to HIV/AIDS patients. This cross-sectional study was on HIV infected adults attending ART clinic in Nigeria to explore nonadherence factors in relation to their socioeconomic characteristics. Validated structured questionnaire was administered to 221 participants. Results showed a high nonadherence rate of 85.1%. The commonest occurring factors of non-adherence were forgetfulness (53.8%), busy schedule (38.8%), side effects of drugs (31.9%), and stigma (31.9%). Males were more likely to complain from busy schedule, feeling healthy, fear of partner disclosure, long waiting period, and long term regimen. Patients with no formal education were more likely to attribute non-adherence to poor communication, side effects of drugs, and stigma. Employed patients seemed to miss their drugs more than the unemployed and artisans. The high non-adherence rate has serious implications for the control of HIV in infected individuals and management of HIV in general. Nurses should intensify efforts on patient education and counseling.

摘要

坚持抗逆转录病毒疗法(ART)的治疗指导对于取得成功的治疗效果至关重要。然而,坚持治疗指导给艾滋病毒/艾滋病患者带来了巨大挑战。这项横断面研究针对在尼日利亚接受抗逆转录病毒治疗门诊的成年艾滋病毒感染者,探讨与他们社会经济特征相关的不坚持治疗因素。对221名参与者进行了经过验证的结构化问卷调查。结果显示不坚持治疗率高达85.1%。最常见的不坚持治疗因素是健忘(53.8%)、日程繁忙(38.8%)、药物副作用(31.9%)和耻辱感(31.9%)。男性更有可能抱怨日程繁忙、感觉健康、害怕向伴侣透露病情、等待时间长以及治疗方案持续时间长。未受过正规教育患者更有可能将不坚持治疗归因于沟通不畅、药物副作用和耻辱感。就业患者似乎比失业者和工匠更容易漏服药物。高不坚持治疗率对受感染个体的艾滋病毒控制以及总体艾滋病毒管理具有严重影响。护士应加大患者教育和咨询力度。