aGlaucoma Center of San Francisco bGlaucoma Research and Education Group, San Francisco, California, USA.
Curr Opin Ophthalmol. 2014 Mar;25(2):98-103. doi: 10.1097/ICU.0000000000000026.
Recent developments in anterior segment imaging enable high-resolution imaging with higher speeds than previous systems. This review will focus on advances in optical coherence tomography (OCT) imaging of the anterior segment with an emphasis on angle evaluation.
Anterior segment imaging with OCT is possible with both time domain and Fourier domain devices, and with light sources of different wavelengths. Recent studies have identified new risk factors for angle closure and prediction models incorporating quantitative angle width parameters have been developed for detection of gonioscopically defined angle closure. Swept source OCT is a variation of Fourier domain OCT that allows three-dimensional imaging of the angle analogous to gonioscopy and novel quantitative parameters have been described for angle measurement with this technology. Fourier domain OCT devices have higher resolution and sampling density than time domain OCT and enable visualization of more angle structures such as the Schwalbe's line and Schlemm's canal.
OCT technology is expanding our understanding of angle closure disease. Although it does not replace gonioscopy in angle evaluation, it may help us identify predictors of progression along the angle closure disease spectrum such that treatment may be better targeted.
前段成像技术的最新进展使得高分辨率成像的速度比以前的系统更快。这篇综述将重点介绍前节 OCT 成像的进展,特别是角度评估。
时域和频域设备以及不同波长的光源都可实现前段成像 OCT。最近的研究确定了房角关闭的新危险因素,并开发了包含定量角度宽度参数的预测模型,用于检测眼前节定量定义的房角关闭。扫频源 OCT 是频域 OCT 的一种变体,可对类似于房角镜的角度进行三维成像,并描述了该技术用于角度测量的新定量参数。与时域 OCT 相比,频域 OCT 具有更高的分辨率和采样密度,可显示更多的角度结构,如 Schwalbe 线和 Schlemm 管。
OCT 技术扩展了我们对房角关闭疾病的认识。尽管它不能替代房角镜在角度评估中的作用,但它可能有助于我们识别房角关闭疾病谱中进展的预测因子,以便更好地针对治疗。