秘鲁利马伤寒沙门氏菌分离株对环丙沙星的中度敏感性。
Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru.
作者信息
García Coralith, Lejon Veerle, Horna Gertrudis, Astocondor Lizeth, Vanhoof Raymond, Bertrand Sophie, Jacobs Jan
机构信息
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
出版信息
J Clin Microbiol. 2014 Mar;52(3):968-70. doi: 10.1128/JCM.02663-13. Epub 2013 Dec 26.
Abstract
Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).
摘要
从秘鲁利马收集的33株肠炎沙门氏菌伤寒血清型血液分离株（2008年至2012年），对甲氧苄啶-磺胺甲恶唑、氯霉素、头孢曲松和四环素完全敏感；8/33（24.2%）对环丙沙星表现出中度敏感性，其gyrA基因（Ser83-Phe和Asp87-Asn）和gyrB基因（Ser464-Phe）的喹诺酮耐药决定区携带突变。
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