Clinic of Anesthesiology and Intensive Therapy, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia ; Faculty of Medicine of the Military Medical Academy, University of Defence, Crnotravska 17, 11000 Belgrade, Serbia.
Clinical Center Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia ; Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, 34000 Kragujevac, Serbia.
Mediators Inflamm. 2013;2013:362793. doi: 10.1155/2013/362793. Epub 2013 Nov 24.
Immunoinflammatory response in critically ill patients is very complex. This review explores some of the new elements of immunoinflammatory response in severe sepsis, tumor necrosis factor-alpha in severe acute pancreatitis as a clinical example of immune response in sepsis, immune response in severe trauma with or without secondary sepsis, and genetic aspects of host immuno-inflammatory response to various insults in critically ill patients.
危重病患者的免疫炎症反应非常复杂。本综述探讨了严重脓毒症中免疫炎症反应的一些新元素、作为脓毒症免疫反应临床范例的严重急性胰腺炎中的肿瘤坏死因子-α、伴或不伴继发脓毒症的严重创伤的免疫反应,以及宿主对危重病患者各种损伤的免疫炎症反应的遗传方面。