Talic Nabeel F, Alnahwi Hasan H, Al-Faraj Ali S
Associate Professor and Consultant Orthodontist, Vice Dean Graduate Studies and Scientific Research, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Pediatric Dentistry Program, University of Texas Health Science Center at San Antonio, United States.
Saudi Dent J. 2013 Oct;25(4):129-33. doi: 10.1016/j.sdentj.2013.10.001. Epub 2013 Oct 19.
The aim of this study was to measure the amount of nickel (Ni) and chromium (Cr) released into the saliva of Saudi patients treated with fixed orthodontic appliances.
Ninety salivary samples were collected in a cross-sectional manner. Forty samples were collected from patients (17 males, 23 females) with fixed orthodontic appliances after different periods of orthodontic treatment ranging from the first month and up to 32 months into treatment. The fixed orthodontic appliance consisted of 4 bands, 20 stainless steel brackets, and upper and lower nickel titanium or stainless-steel arch wires. The other 50 samples were collected from people without appliances (24 males, 26 females). Samples were analyzed using Inductive Coupled Plasma/Mass Spectrometry and Inductively Coupled Plasma Optical Emission Spectroscopy to measure Ni and Cr levels, respectively. Student's t-test was used to compare Ni and Cr levels in the treated and untreated control groups.
The mean Ni level was 4.197 μg/L in the experimental group and 2.3 μg/L in the control group (p < 0.05). The mean Cr level was 2.9 μg/L in the experimental group and 3.3 μg/L in the control group (p < 0.05).
Fixed orthodontic appliances resulted in a non-toxic increase in salivary levels of Ni, but no change in Cr levels. Duration of orthodontic treatment did not affect Ni and Cr levels in the saliva.
本研究旨在测量接受固定正畸矫治器治疗的沙特患者唾液中释放的镍（Ni）和铬（Cr）含量。
以横断面方式收集90份唾液样本。40份样本来自接受固定正畸矫治器治疗的患者（17名男性，23名女性），正畸治疗时间从第1个月至治疗32个月不等。固定正畸矫治器由4个带环、20个不锈钢托槽以及上下镍钛或不锈钢弓丝组成。另外50份样本来自未佩戴矫治器的人群（24名男性，26名女性）。分别使用电感耦合等离子体质谱法和电感耦合等离子体发射光谱法分析样本，以测量镍和铬的水平。采用学生t检验比较治疗组和未治疗对照组中镍和铬的水平。
实验组镍的平均水平为4.197μg/L，对照组为2.3μg/L（p<0.05）。实验组铬的平均水平为2.9μg/L，对照组为3.3μg/L（p<0.05）。
固定正畸矫治器导致唾液中镍含量无毒增加，但铬含量无变化。正畸治疗时间未影响唾液中镍和铬的水平。
