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本文引用的文献

1
Impaired left ventricular systolic function reserve limits cardiac output and exercise capacity in HFpEF patients due to systemic hypertension.由于高血压,HFpEF 患者左心室收缩功能储备受损会限制心输出量和运动能力。
Int J Cardiol. 2013 Sep 30;168(2):1088-93. doi: 10.1016/j.ijcard.2012.11.035. Epub 2012 Nov 22.
2
Cumulative impact of cardiovascular risk factors on regional left ventricular function and reserve: progressive long-axis dysfunction with compensatory radial changes.心血管危险因素对局部左心室功能及储备的累积影响:伴有代偿性径向改变的进行性长轴功能障碍。
Echocardiography. 2011 Sep;28(8):813-20. doi: 10.1111/j.1540-8175.2011.01456.x. Epub 2011 Aug 9.
3
Established and novel clinical applications of diastolic function assessment by echocardiography.超声心动图评估舒张功能的既定及新临床应用
Circ Cardiovasc Imaging. 2011 Jul;4(4):444-55. doi: 10.1161/CIRCIMAGING.110.961623.
4
Reversal of subclinical left ventricular dysfunction by antihypertensive treatment: a prospective trial of nebivolol against metoprolol.血管紧张素转换酶抑制剂对左心室肥厚及心功能的影响
J Hypertens. 2011 Apr;29(4):809-17. doi: 10.1097/HJH.0b013e3283442f37.
5
The concept of ventricular reserve in heart failure and pulmonary hypertension: an old metric that brings us one step closer in our quest for prediction.心力衰竭和肺动脉高压中心室储备的概念:一个古老的指标,在我们的预测探索中又迈进了一步。
Curr Opin Cardiol. 2011 Mar;26(2):123-31. doi: 10.1097/HCO.0b013e3283437485.
6
Assessment of myocardial viability at dobutamine echocardiography by deformation analysis using tissue velocity and speckle-tracking.应用组织速度和斑点追踪技术的应变分析评估多巴酚丁胺超声心动图中的心肌存活性。
JACC Cardiovasc Imaging. 2010 Feb;3(2):121-31. doi: 10.1016/j.jcmg.2009.09.025.
7
Contractile reserve: are we beginning to understand it?收缩储备:我们开始理解它了吗?
JACC Cardiovasc Imaging. 2008 Nov;1(6):727-8. doi: 10.1016/j.jcmg.2008.09.001.
8
Importance of left ventricular longitudinal function and functional reserve in patients with degenerative mitral regurgitation: assessment by two-dimensional speckle tracking.左心室纵向功能和功能储备在退行性二尖瓣反流患者中的重要性:二维斑点追踪评估
J Am Soc Echocardiogr. 2008 Dec;21(12):1331-6. doi: 10.1016/j.echo.2008.09.023.
9
American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography.美国超声心动图学会关于负荷超声心动图的操作、解读及应用的建议。
J Am Soc Echocardiogr. 2007 Sep;20(9):1021-41. doi: 10.1016/j.echo.2007.07.003.
10
Ethnic differences in arterial stiffness and wave reflections after cigarette smoking.吸烟后动脉僵硬度和波反射的种族差异。
J Hypertens. 2006 Apr;24(4):683-9. doi: 10.1097/01.hjh.0000217850.87960.16.

高血压患者中超越传统指标的收缩期和舒张期心脏功能评估。心脏储备的作用。

Assessment of Systolic and Diastolic Cardiac Function beyond Traditional Markers in Hypertensive Patients. Role of Cardiac Reserve.

作者信息

Patrascu Natalia

机构信息

"Carol Davila" University of Medicine and Pharmacy, Cardiology Department, University Emergency Hospital, Bucharest, Romania.

出版信息

Maedica (Bucur). 2013 Jun;8(2):214-9.

PMID:24371488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3865133/
Abstract

BACKGROUND

the mechanical performance of the cardiac pump should be evaluated not only at rest but also in relation to its response to peak stimulation, since the earliest consequence of the cardiac pump capacity in the evolution of heart failure is the decrease of the maximal performance. This can be assessed by measuring the cardiac functional reserve, usually by a physical or a pharmacological stress test combined with echocardiography imaging.Content and comments: in symptomatic heart failure, the main purpose is to objectively identify the point to which the impairment of the pump function is irreversible. Moreover, there is growing evidence that the functional systolic and diastolic reserve is decreased even in the early, subclinical stages of cardiac dysfunction that exists for example in hypertensive disease and that the decrease seems to be related to the number of the associated cardiovascular risk factors.

CONCLUSION

thus, better preventive and therapeutic strategies could be established by detecting a reduced functional reserve in this category of patients at high risk of heart failure development, with important public-health implications.

摘要

背景

心脏泵的机械性能不仅应在静息状态下评估,还应根据其对峰值刺激的反应进行评估,因为在心力衰竭发展过程中,心脏泵功能最早出现的后果是最大性能的下降。这可以通过测量心脏功能储备来评估,通常是通过体格检查或药物负荷试验结合超声心动图成像来进行。内容与评论:在有症状的心力衰竭中,主要目的是客观地确定泵功能损害到何种程度是不可逆的。此外,越来越多的证据表明,即使在心脏功能障碍的早期亚临床阶段,如高血压疾病中,功能性收缩和舒张储备也会降低,而且这种降低似乎与相关心血管危险因素的数量有关。

结论

因此,通过检测这类有心力衰竭发生高风险患者的功能储备降低情况,可以制定更好的预防和治疗策略,这具有重要的公共卫生意义。