Patrascu Natalia
"Carol Davila" University of Medicine and Pharmacy, Cardiology Department, University Emergency Hospital, Bucharest, Romania.
Maedica (Bucur). 2013 Jun;8(2):214-9.
the mechanical performance of the cardiac pump should be evaluated not only at rest but also in relation to its response to peak stimulation, since the earliest consequence of the cardiac pump capacity in the evolution of heart failure is the decrease of the maximal performance. This can be assessed by measuring the cardiac functional reserve, usually by a physical or a pharmacological stress test combined with echocardiography imaging.Content and comments: in symptomatic heart failure, the main purpose is to objectively identify the point to which the impairment of the pump function is irreversible. Moreover, there is growing evidence that the functional systolic and diastolic reserve is decreased even in the early, subclinical stages of cardiac dysfunction that exists for example in hypertensive disease and that the decrease seems to be related to the number of the associated cardiovascular risk factors.
thus, better preventive and therapeutic strategies could be established by detecting a reduced functional reserve in this category of patients at high risk of heart failure development, with important public-health implications.
心脏泵的机械性能不仅应在静息状态下评估,还应根据其对峰值刺激的反应进行评估,因为在心力衰竭发展过程中,心脏泵功能最早出现的后果是最大性能的下降。这可以通过测量心脏功能储备来评估,通常是通过体格检查或药物负荷试验结合超声心动图成像来进行。内容与评论:在有症状的心力衰竭中,主要目的是客观地确定泵功能损害到何种程度是不可逆的。此外,越来越多的证据表明,即使在心脏功能障碍的早期亚临床阶段,如高血压疾病中,功能性收缩和舒张储备也会降低,而且这种降低似乎与相关心血管危险因素的数量有关。
因此,通过检测这类有心力衰竭发生高风险患者的功能储备降低情况,可以制定更好的预防和治疗策略,这具有重要的公共卫生意义。