术后晚期黄曲霉心内膜炎：利用微卫星分型证明六年潜伏期
Late post-operative Aspergillus flavus endocarditis: Demonstration of a six years incubation period using microsatellite typing.
作者信息
Dupouey Julien, Faucher Benoit, Normand Anne-Cécile, Hadrich Inès, Ranque Stéphane, Dumon Henri, Casalta Jean-Paul, Collart Frédéric, Piarroux Renaud
机构信息
Laboratoire de Parasitologie et mycologie, Centre Hospitalo-Universitaire Timone, 264 rue Saint-Pierre 13385, Marseille Cedex 05, France.
Laboratoire de Parasitologie et mycologie, Centre Hospitalo-Universitaire Timone, 264 rue Saint-Pierre 13385, Marseille Cedex 05, France ; Université de la Méditerranée, UMR MD3, Marseille, France.
出版信息
Med Mycol Case Rep. 2012 May 24;1(1):29-31. doi: 10.1016/j.mmcr.2012.05.001. eCollection 2012.
Abstract
Late post-operative Aspergillus endocarditis is an under recognized life-threatening complication of heart valvular surgery. Optimal prevention and treatment need enhanced awareness. We report three cases of post-operative Aspergillus flavus endocarditis, including one with a 6-year long incubation period. Microsatellite typing incriminated a recurrent contamination of hospital environment.
摘要
术后晚期曲霉菌性心内膜炎是心脏瓣膜手术一种未得到充分认识的危及生命的并发症。最佳的预防和治疗需要提高认识。我们报告三例术后黄曲霉菌性心内膜炎病例，其中一例潜伏期长达6年。微卫星分型表明医院环境存在反复污染。
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