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草药使用的安全性:尼日利亚拉各斯伊科罗杜居民的案例研究

Safety of herbal medicines use: case study of ikorodu residents in Lagos, Nigeria.

作者信息

Awodele Olufunsho, Amagon Kennedy I, Usman Sikiru O, Obasi Precious C

机构信息

Department of Pharmacology, Therapeutics & Toxicology, College of Medicine, University of Lagos, P.M.B 12003, Nigeria.

出版信息

Curr Drug Saf. 2014;9(2):138-44. doi: 10.2174/1574886308666131229104104.

Abstract

BACKGROUND

Despite the reported widespread use of herbal medicines globally and their benefits, they are not completely without potential to cause harm. The haphazard, irresponsible or non-regulated use of several herbal medicines may put the health of their users at risk of toxicity.

OBJECTIVE

This study aimed to assess the general perception of the safety and occurrence of adverse effects of herbal medicines among residents of Ikorodu in Lagos, Nigeria.

METHODS

The study population included 400 randomly selected and consented residents in Ikorodu. Data was collected using a standard closed and open-ended structured questionnaire with three (3) sections on socio-demography, safety and adverse effects of herbal medicines. Associations between the variables were determined using Chi square analysis.

RESULTS

The results showed that 333 respondents (82.4%) believed that herbal medicines are safe for use and only 39 (9.7%) held the view that they may not be safe. RESULTS also show that 51 (12.6%) of respondents had experienced adverse effects while 250 (61.9%) said they had never experienced adverse effects from the use of herbal medicines.

CONCLUSION

Herbal medicine is popular among the respondents but they appear to be ignorant of its potential toxicities. It may be necessary to educate the consumers of herbal medicines on the potentials for herbs-drugs interaction and adverse effects specially as a result of indiscriminate and unguided use of herbal medicines.

摘要

背景

尽管有报道称草药在全球广泛使用且具有益处,但它们并非完全没有造成伤害的可能性。几种草药的随意、不负责任或无监管使用可能会使使用者的健康面临中毒风险。

目的

本研究旨在评估尼日利亚拉各斯伊科罗杜居民对草药安全性及不良反应发生情况的总体认知。

方法

研究人群包括伊科罗杜随机选取并同意参与的400名居民。使用标准的封闭式和开放式结构化问卷收集数据,问卷有关于社会人口统计学、草药安全性及不良反应的三个部分。使用卡方分析确定变量之间的关联。

结果

结果显示,333名受访者(82.4%)认为草药使用安全,只有39人(9.7%)认为其可能不安全。结果还显示,51名受访者(12.6%)曾经历过不良反应,而250人(61.9%)表示他们从未因使用草药而经历过不良反应。

结论

草药在受访者中很受欢迎,但他们似乎对其潜在毒性一无所知。可能有必要对草药消费者进行教育,使其了解草药与药物相互作用的可能性以及特别是由于随意和无指导使用草药而产生的不良反应。

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