McCormick K B
J Neurosci Nurs. 1987 Apr;19(2):66-76. doi: 10.1097/01376517-198704000-00002.
Pregnant women with epilepsy have a greater risk for complications of pregnancy and adverse pregnancy outcomes. Problems that may arise during the course of pregnancy include an increase in seizure frequency, reduction of serum antiepileptic drug levels, and an increase in bleeding during pregnancy and after delivery. The infant of an epileptic mother is at twice the risk of infants in the general population to have a major malformation, and the risk for perinatal death is 1.2 to 3 times greater. Despite these facts, at least 90% of women with epilepsy have a normal pregnancy and deliver a normal infant. The pregnant woman with epilepsy may minimize the risk of adverse outcome by taking measures to ensure an optimal prenatal course. The neuroscience nurse can provide these clients with accurate information regarding pregnancy and epilepsy and can review measures that may be taken to reduce chances of an unfavorable outcome.
患有癫痫的孕妇出现妊娠并发症和不良妊娠结局的风险更高。孕期可能出现的问题包括癫痫发作频率增加、血清抗癫痫药物水平降低以及孕期和分娩后出血增加。癫痫母亲所生婴儿出现严重畸形的风险是普通人群婴儿的两倍,围产期死亡风险则高1.2至3倍。尽管如此,至少90%的癫痫女性怀孕正常且分娩出正常婴儿。患有癫痫的孕妇可通过采取措施确保最佳的产前过程,将不良结局的风险降至最低。神经科学护士可以为这些患者提供有关妊娠和癫痫的准确信息,并可审查为降低不良结局可能性而可能采取的措施。