Department of Psychiatry, Obsessive-Compulsive Disorder (OCD) Clinic, National Institute of Mental Health and NeuroSciences (NIMHANS), Bangalore, India-560029.
Expert Rev Neurother. 2014 Feb;14(2):151-63. doi: 10.1586/14737175.2014.874287. Epub 2013 Dec 27.
Obsessive-compulsive disorder (OCD) is a common and often a highly disabling condition that was considered untreatable before the 1960s. The advent of serotonin reuptake inhibitors and exposure and response prevention revolutionized the treatment of OCD. Although they are still the first line treatments for OCD, new treatments like augmentation strategies, brain stimulation techniques, psychosurgery, newer forms of psychotherapy (like cognitive therapy, acceptance and commitment therapy) have been added to the armamentarium. With the available treatment strategies, many patients can achieve at least partial remission of symptoms. Nevertheless, the plethora of information gives rise to many questions on their application for practicing clinicians. We provide evidence-based responses to these questions and suggest a broad guideline for treatment of OCD.
强迫症（OCD）是一种常见且常常严重致残的疾病，在 20 世纪 60 年代之前被认为是无法治疗的。血清素再摄取抑制剂和暴露与反应预防的出现彻底改变了 OCD 的治疗方法。虽然它们仍然是 OCD 的一线治疗方法，但新的治疗方法，如增效策略、脑刺激技术、精神外科、更新形式的心理治疗（如认知疗法、接受与承诺疗法）也已加入治疗方案中。有了现有的治疗策略，许多患者的症状至少可以部分缓解。然而，大量的信息引发了许多关于其在实践临床医生中应用的问题。我们对这些问题提供了循证的回答，并为 OCD 的治疗提出了一个广泛的指导原则。
