Programa de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, BA, Brazil. Laboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Laboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Trends Psychiatry Psychother. 2023;45:e20210247. doi: 10.47626/2237-6089-2021-0247. Epub 2022 May 25.
Obsessive-compulsive disorder (OCD) is the fourth most prevalent mental disorder and is a disabling condition. OCD is associated with anatomical and functional changes in the brain, in addition to dysfunctional cognitions. The treatments of choice are selective serotonin reuptake inhibitors, cognitive-behavioral therapy (CBT), and exposure and response prevention (ERP). Trial-based cognitive therapy (TBCT) is a recent and empirically validated psychotherapy with a focus on restructuring dysfunctional negative core beliefs (CBs). The objective of this study was to evaluate the efficacy of TBCT relative to ERP for treatment of OCD.
A randomized, single-blind clinical trial was conducted, randomizing 26 patients for individual treatment with TBCT (n = 12) or ERP (n = 14). The groups were evaluated at baseline, at the end of 3 months (12 sessions), and at 3, 6, and 12-month follow-ups.
Both approaches reduced the severity of symptoms with large effect sizes. These results were maintained at the 12-month follow-up assessment.
TBCT may be a valid and promising treatment for this disorder.
强迫症（OCD）是第四大常见精神障碍，也是一种使人丧失能力的疾病。除了认知功能障碍外，强迫症还与大脑的解剖和功能变化有关。首选的治疗方法是选择性 5-羟色胺再摄取抑制剂、认知行为疗法（CBT）和暴露与反应预防（ERP）。基于试验的认知疗法（TBCT）是一种最近的、经过实证验证的心理治疗方法，侧重于重构功能失调的消极核心信念（CBs）。本研究的目的是评估 TBCT 相对于 ERP 治疗 OCD 的疗效。
进行了一项随机、单盲临床试验，将 26 名患者随机分为接受个体 TBCT（n=12）或 ERP（n=14）治疗的两组。两组在基线、3 个月（12 次治疗）结束时，以及 3、6 和 12 个月随访时进行评估。
两种方法都降低了症状的严重程度，效果显著。这些结果在 12 个月的随访评估中得到了维持。
TBCT 可能是治疗这种疾病的一种有效且有前途的方法。
