Rolland C, Johnston K L, Lula S, Macdonald I, Broom J
Centre for Obesity Research and Epidemiology, Robert Gordon University, Aberdeen, UK.
Int J Clin Pract. 2014 Mar;68(3):379-87. doi: 10.1111/ijcp.12300. Epub 2013 Dec 22.
Effective weight loss treatment is important as obesity has severe health and socioeconomic repercussions. Emerging evidence suggests that rapid initial weight loss results in better long-term weight loss maintenance. This remains controversial and contradicts current recommendations for slower weight loss.
To determine the effect of a very low calorie diet (VLCD) with group-based behaviour therapy on weight loss and long-term weight management by means of a retrospective database analysis.
Data for this retrospective analysis included participants who embarked on the LighterLife Total VLCD programme between 2007 and 2010, and whose weights at baseline and at least 12 months were available (n = 5965).
Data were available for 5965 individuals at 1 year, 2044 at 2 years and 580 at 3 years. At baseline, the majority of individuals were Caucasian (n = 5155), female (n = 5419), ≥ 40 years old (n = 4272), 49% were within the body mass index (BMI) range of 30-35 kg/m(2) while 51% had a BMI > 35 kg/m(2) . The average initial weight of the whole cohort was 99.1 kg (SD 16.6). Initial weight and BMI at entry onto programme, as well as numbers of weeks of weight loss were all significantly associated with weight loss achieved on the first weight loss attempt. Weight lost during the initial weight loss phase was the only factor, which was significantly associated with percentage weight loss maintenance for years 1, 2, and 3.
The findings of this retrospective analysis suggest that provided a longer term weight loss management programme is adhered to, large amounts of initial weight loss can result in important longer term weight loss maintenance in motivated individuals.
由于肥胖会对健康和社会经济产生严重影响,有效的减肥治疗至关重要。新出现的证据表明,最初快速减重能带来更好的长期体重维持效果。这一观点仍存在争议,且与当前关于缓慢减重的建议相矛盾。
通过回顾性数据库分析,确定极低热量饮食(VLCD)结合基于小组的行为疗法对体重减轻及长期体重管理的影响。
此次回顾性分析的数据包括2007年至2010年间开始参加轻生活全极低热量饮食计划且有基线体重和至少12个月体重数据的参与者(n = 5965)。
1年时有5965人的数据可用,2年时有2044人的数据可用,3年时有580人的数据可用。基线时,大多数个体为白种人(n = 5155)、女性(n = 5419)、年龄≥40岁(n = 4272),49%的人体重指数(BMI)在30 - 35 kg/m²范围内,51%的人BMI > 35 kg/m²。整个队列的平均初始体重为99.1 kg(标准差16.6)。开始计划时的初始体重和BMI以及减重周数均与首次减重尝试时的体重减轻显著相关。初始减重阶段减轻的体重是与第1年、第2年和第3年体重减轻维持百分比显著相关的唯一因素。
这项回顾性分析的结果表明,倘若坚持长期的体重管理计划,大量的初始体重减轻可使有积极性的个体实现重要的长期体重维持。