Pekkarinen T, Takala I, Mustajoki P
Department of Medicine, Helsinki University Hospital, Finland.
Int J Obes Relat Metab Disord. 1996 Apr;20(4):332-7.
To investigate changes in weight, Three Factor Eating Questionnaire and Binge eating scores during a two-year period from the start of a VLCD (Nutrilett) and behavioural modification therapy for obesity.
Prospective study of a 17-weeks weight loss programme with one- and two-year follow-up visits.
62 healthy, overweight subjects without previous eating disorders. The mean (+/- SD) age 41 +/- 8 years and BMI 36.4 +/- 2.6 kg/m2.
Weight loss, Binge eating scale, Bulimic Investigatory Test and Three Factor Eating Questionnaire before and after therapy and at 1 and 2 year control visits.
The mean weight loss (+/- SD) at the end of the treatment was 14.9 +/- 4.6 kg (n = 59) and at the two-year control 5.8 +/- 7.6 kg (n = 57). After two years 20 (32%) patients had a weight loss of more than 10% (good result), 24 patients a weight loss of 0-10% of their initial weight (partial result) and 13 patients weighed more than before therapy (poor result). The mean binge eating, disinhibition and hunger scores decreased in all patients by the end of the therapy. At the end of two years these improvements in the scores were maintained in patients with a good result but the scores returned to the pretreatment levels in the patients with partial or poor result. The mean restraint scores increased in all patients after treatment and were maintained in those with a good or partial result.
VLCD combined with behaviour modification is a useful mode of therapy for obesity with low drop-out rate and majority (71%) of patients below pretreatment weight at the two-year control. One third of the patients succeeded to maintain positive changes in the scores measuring eating behaviour which was associated with sustained weight loss.
调查从极低热量饮食(Nutrilett)和肥胖行为矫正治疗开始的两年期间,体重、三因素饮食问卷及暴饮暴食得分的变化情况。
一项为期17周的减肥计划的前瞻性研究,随访1年和2年。
62名无既往饮食失调史的健康超重受试者。平均(±标准差)年龄41±8岁,体重指数36.4±2.6kg/m²。
治疗前后及1年和2年对照访视时的体重减轻情况、暴饮暴食量表、贪食症调查测试及三因素饮食问卷。
治疗结束时平均体重减轻(±标准差)为14.9±4.6kg(n = 59),两年对照时为5.8±7.6kg(n = 57)。两年后,20名(32%)患者体重减轻超过10%(效果良好),24名患者体重减轻了初始体重的0 - 10%(部分效果),13名患者体重比治疗前更重(效果不佳)。所有患者在治疗结束时,平均暴饮暴食、去抑制和饥饿得分均下降。两年结束时,效果良好的患者这些得分的改善得以维持,但部分效果或效果不佳的患者得分恢复到治疗前水平。所有患者治疗后平均克制得分增加,效果良好或部分效果的患者得分得以维持。
极低热量饮食联合行为矫正治疗肥胖是一种有用的治疗方式,脱落率低,两年对照时大多数(71%)患者体重低于治疗前。三分之一的患者成功维持了测量饮食行为得分的积极变化,这与持续体重减轻相关。