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胸椎间盘突出症的前路还是后路手术?微创经胸椎间盘切除术与经椎弓根椎间盘切除术的比较队列研究

Anterior or posterior approach of thoracic disc herniation? A comparative cohort of mini-transthoracic versus transpedicular discectomies.

作者信息

Arts Mark P, Bartels Ronald H M A

机构信息

Department of Neurosurgery, Medical Center Haaglanden, PO Box 432, 2501 CK, The Hague, The Netherlands.

Department of Neurosurgery, Radboud University Medical Center Nijmegen, PO Box 9101, 6500HB, Nijmegen, The Netherlands.

出版信息

Spine J. 2014 Aug 1;14(8):1654-62. doi: 10.1016/j.spinee.2013.09.053. Epub 2013 Oct 24.

Abstract

BACKGROUND CONTEXT

The optimal surgical treatment of thoracic disc herniations remains controversial and depends on the consistency of the herniation and its location related to the spinal cord.

PURPOSE

To compare the outcomes of patients with symptomatic thoracic disc herniations treated with anterolateral mini-transthoracic approach (TTA) versus posterior transpedicular discectomy.

STUDY DESIGN

This is a prospective comparative cohort study.

PATIENT SAMPLE

One hundred consecutive patients with symptomatic thoracic herniated discs were operated by mini-TTA (56 patients) or transpedicular discectomy (44 patients).

OUTCOME MEASURES

Neurologic assessment by American Spinal Injury Association (ASIA) Impairment Scale and patients' self reported perceived recovery and complications.

METHODS

The consistency and location of the herniated disc in relation to the spinal cord was evaluated by preoperative computed tomography and magnetic resonance imaging. Patients were assessed neurologically before surgery and at regular outpatient controls at 2 months or later. Long-term follow-up was achieved by questionnaires sent by mail.

RESULTS

In both groups, most patients had symptoms of myelopathy and radicular pain; patients who underwent mini-TTA, more frequently suffered from spasticity. Fifty-eight percent of the herniated discs were calcified and 77% were larger than one-third of the spinal canal. All patients presented with ASIA Grade C or D (64%) or ASIA Grade E (36%). Postoperatively, 50% of the patients treated with mini-TTA and 37% of the transpedicular group improved at least one grade on the ASIA scale (p=.19). The duration of surgery, blood loss, hospital stay, and complication rate were significantly higher in patients treated with mini-TTA and were mainly related to the magnitude and consistency of the herniated disc. At long-term follow-up, 72% of the mini-TTA patients reported good outcome versus 76% of the transpedicular discectomy group (p=.80).

CONCLUSIONS

Surgical treatment of a symptomatic herniated disc contributed to a clinical improvement in most cases. The approach is dependent on the location, the magnitude, and the consistency of the herniated thoracic disc. Medially located large calcified discs should be operated through an anterolateral approach, whereas noncalcified or lateral herniated discs can be treated from a posterior approach as well. For optimal treatment of this rare entity, the treatment should be performed in selected centers.

摘要

背景

胸椎间盘突出症的最佳手术治疗方案仍存在争议,这取决于椎间盘突出的程度及其与脊髓的位置关系。

目的

比较采用前外侧经胸小切口入路(TTA)与后路经椎弓根椎间盘切除术治疗有症状的胸椎间盘突出症患者的疗效。

研究设计

这是一项前瞻性比较队列研究。

患者样本

连续100例有症状的胸椎间盘突出症患者接受了经胸小切口入路手术(56例)或经椎弓根椎间盘切除术(44例)。

观察指标

采用美国脊髓损伤协会(ASIA)损伤量表进行神经功能评估,以及患者自我报告的恢复情况和并发症。

方法

术前通过计算机断层扫描和磁共振成像评估椎间盘突出与脊髓的程度及位置关系。术前及术后2个月或更晚的定期门诊复查时对患者进行神经功能评估。通过邮寄问卷进行长期随访。

结果

两组中,大多数患者有脊髓病和神经根性疼痛症状;接受经胸小切口入路手术的患者痉挛更为常见。58%的椎间盘突出有钙化,77%的突出物大于椎管的三分之一。所有患者的ASIA分级为C级或D级(64%)或ASIA E级(36%)。术后,经胸小切口入路手术治疗的患者中有50%、经椎弓根手术组中有37%在ASIA量表上至少提高了一个等级(p = 0.19)。经胸小切口入路手术患者的手术时间、失血量、住院时间和并发症发生率显著更高,且主要与椎间盘突出的程度和质地有关。在长期随访中,经胸小切口入路手术患者中有72%报告预后良好,经椎弓根椎间盘切除术组为76%(p = 0.80)。

结论

大多数情况下,有症状的椎间盘突出症的手术治疗有助于临床改善。手术入路取决于胸椎间盘突出的位置、程度和质地。位于中央的大型钙化椎间盘应采用前外侧入路手术,而非钙化或外侧椎间盘突出也可采用后路治疗。为了对这种罕见疾病进行最佳治疗,应在选定的中心进行治疗。

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