Stenberg Erik, Szabo Eva, Agren Göran, Näslund Erik, Boman Lars, Bylund Ami, Hedenbro Jan, Laurenius Anna, Lundegårdh Göran, Lönroth Hans, Möller Peter, Sundbom Magnus, Ottosson Johan, Näslund Ingmar
*Department of Surgery, Lindesberg Hospital, Lindesberg, Sweden †Department of Surgery, Örebro University Hospital, Örebro, Sweden ‡Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden §Department of Surgery, Lycksele Hospital, Lycksele, Sweden ¶Department of Surgery, Ersta Hospital, Stockholm, Sweden ‖Skåne University Hospital, Lund University, Lund, Sweden **Department of Surgery, Aleris Obesity Skåne, Lund, Sweden ††Department of Surgery, Sahlgrenska University Hospital, Gastrosurgical Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ‡‡Österlenskirurgin, Simrishamn Hospital, Simrishamn, Sweden §§Department of Surgery, Kalmar County Hospital, Kalmar, Sweden; and ¶¶Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Ann Surg. 2014 Dec;260(6):1040-7. doi: 10.1097/SLA.0000000000000431.
To identify risk factors for serious and specific early complications of laparoscopic gastric bypass surgery using a large national cohort of patients.
Bariatric procedures are among the most common surgical procedures today. There is, however, still a need to identify preoperative and intraoperative risk factors for serious complications.
From the Scandinavian Obesity Surgery Registry database, we identified 26,173 patients undergoing primary laparoscopic gastric bypass operation for morbid obesity between May 1, 2007, and September 30, 2012. Follow-up on day 30 was 95.7%. Preoperative data and data from the operation were analyzed against serious postoperative complications and specific complications.
The overall risk of serious postoperative complications was 3.4%. Age (adjusted P = 0.028), other additional operation [odds ratio (OR) = 1.50; confidence interval (CI): 1.04-2.18], intraoperative adverse event (OR = 2.63; 1.89-3.66), and conversion to open surgery (OR = 4.12; CI: 2.47-6.89) were all risk factors for serious postoperative complications. Annual hospital volume affected the rate of serious postoperative complications. If the hospital was in a learning curve at the time of the operation, the risk for serious postoperative complications was higher (OR = 1.45; CI: 1.22-1.71). The 90-day mortality rate was 0.04%.
Intraoperative adverse events and conversion to open surgery are the strongest risk factors for serious complications after laparoscopic gastric bypass surgery. Annual operative volume and total institutional experience are important for the outcome. Patient related factors, in particular age, also increased the risk but to a lesser extent.
利用一个大型全国患者队列确定腹腔镜胃旁路手术严重且特定早期并发症的危险因素。
减肥手术是当今最常见的外科手术之一。然而,仍有必要确定严重并发症的术前和术中危险因素。
从斯堪的纳维亚肥胖手术注册数据库中,我们确定了2007年5月1日至2012年9月30日期间接受初次腹腔镜胃旁路手术治疗病态肥胖的26173例患者。30天的随访率为95.7%。对术前数据和手术数据进行分析,以评估术后严重并发症和特定并发症。
术后严重并发症的总体风险为3.4%。年龄(校正P = 0.028)、其他附加手术[比值比(OR)= 1.50;置信区间(CI):1.04 - 2.18]、术中不良事件(OR = 2.63;1.89 - 3.66)以及转为开放手术(OR = 4.12;CI:2.47 - 6.89)均为术后严重并发症的危险因素。年度医院手术量影响术后严重并发症的发生率。如果手术时医院处于学习曲线阶段,术后严重并发症的风险更高(OR = 1.45;CI:1.22 - 1.71)。90天死亡率为0.04%。
术中不良事件和转为开放手术是腹腔镜胃旁路手术后严重并发症的最强危险因素。年度手术量和机构总体经验对手术结果很重要。与患者相关的因素,尤其是年龄,也会增加风险,但程度较小。