Kallem Radhakrishna R, Meyers Kevin E C, Cucchiara Andrew J, Sawinski Deirdre L, Townsend Raymond R
aDepartment of Medicine, Renal, Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine bDivision of Nephrology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Blood Press Monit. 2014 Apr;19(2):98-102. doi: 10.1097/MBP.0000000000000019.
There are no data on the evaluation of blood pressure (BP) variability comparing two ambulatory blood pressure monitoring monitors worn at the same time. Hence, this study was carried out to compare variability of BP in healthy untreated adults using two ambulatory BP monitors worn at the same time over an 8-h period.
An Accutorr device was used to measure office BP in the dominant and nondominant arms of 24 participants.Simultaneous 8-h BP and heart rate data were measured in 24 untreated adult volunteers by Mobil-O-Graph (worn for an additional 16 h after removing the Spacelabs monitor) and Spacelabs with both random (N=12) and nonrandom (N=12) assignment of each device to the dominant arm. Average real variability (ARV), SD, coefficient of variation, and variation independent of mean were calculated for systolic blood pressure, diastolic blood pressure, mean arterial pressure, and pulse pressure (PP).
Whether the Mobil-O-Graph was applied to the dominant or the nondominant arm, the ARV of mean systolic (P=0.003 nonrandomized; P=0.010 randomized) and PP (P=0.009 nonrandomized; P=0.005 randomized) remained significantly higher than the Spacelabs device, whereas the ARV of the mean arterial pressure was not significantly different. The average BP readings and ARVs for systolic blood pressure and PP obtained by the Mobil-O-Graph were considerably higher for the daytime than the night-time.
Given the emerging interest in the effect of BP variability on health outcomes, the accuracy of its measurement is important. Our study raises concerns about the accuracy of pooling international ambulatory blood pressure monitoring variability data using different devices.
尚无关于同时佩戴两台动态血压监测仪评估血压（BP）变异性的数据。因此，本研究旨在比较健康未治疗成年人在8小时内同时佩戴两台动态血压监测仪时的血压变异性。
使用Accutorr设备测量24名参与者优势臂和非优势臂的诊室血压。24名未治疗的成年志愿者通过Mobil-O-Graph（在移除Spacelabs监测仪后再佩戴16小时）和Spacelabs同时测量8小时的血压和心率数据，每种设备随机（N = 12）和非随机（N = 12）分配至优势臂。计算收缩压、舒张压、平均动脉压和脉压（PP）的平均实际变异性（ARV）、标准差、变异系数和独立于均值的变异。
无论Mobil-O-Graph应用于优势臂还是非优势臂，平均收缩压（非随机分组P = 0.003；随机分组P = 0.010）和PP（非随机分组P = 0.009；随机分组P = 0.005）的ARV均显著高于Spacelabs设备，而平均动脉压的ARV无显著差异。Mobil-O-Graph测得的白天收缩压和PP的平均血压读数及ARV显著高于夜间。
鉴于血压变异性对健康结局的影响日益受到关注，其测量准确性至关重要。我们的研究引发了对使用不同设备汇总国际动态血压监测变异性数据准确性的担忧。
