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切开复位内固定术与全肘关节置换术治疗老年肱骨远端骨折的系统评价与Meta分析

Open Reduction and Internal Fixation Versus Total Elbow Arthroplasty for the Treatment of Geriatric Distal Humerus Fractures: A Systematic Review and Meta-Analysis.

作者信息

Githens Michael, Yao Jeffrey, Sox Alex H S, Bishop Julius

机构信息

Department of Orthopaedics, Stanford University, Redwood City, CA.

出版信息

J Orthop Trauma. 2014 Aug;28(8):481-8. doi: 10.1097/BOT.0000000000000050.

DOI:10.1097/BOT.0000000000000050
PMID:24375273
Abstract

OBJECTIVES

The purpose of this systematic review and meta-analysis was to pool and analyze outcomes and complication rates in elderly patients with intraarticular distal humerus fractures being treated with either total elbow arthroplasty (TEA) or open reduction and internal fixation (ORIF) with locking plates.

DATA SOURCES

PubMed, Embase, and the Cochrane databases were used. The search included publications up to June 2013. Article selection was independently performed by 2 authors and disagreements were resolved by consensus.

STUDY SELECTION

Studies meeting criteria for inclusion were observational cohort studies or randomized controlled trials evaluating functional and radiographic outcomes and complications in elderly patients treated for distal humerus fractures with either primary TEA or ORIF with locking plates. Studies with mean age <60 years, indications for TEA other than acute fracture, and those including nonlocked plates were excluded.

DATA EXTRACTION

Standardized data extraction was performed. A quality assessment tool was used to evaluate individual study methodology.

DATA SYNTHESIS

Descriptive statistics for functional outcomes were reported. Meta-analysis and regression analysis were performed for complication rates.

CONCLUSIONS

A systematic review and meta-analysis revealed that TEA and ORIF for the treatment of geriatric distal humerus fractures produced similar functional outcome scores and range of motion. Although there was a trend toward a higher rate of major complications and reoperation after ORIF, this was not statistically significant. The quality of study methodology was generally weak. Ongoing research including prospective trials and cost analysis is indicated to better define the roles of ORIF versus TEA in the management of these injuries.

摘要

目的

本系统评价和荟萃分析的目的是汇总并分析采用全肘关节置换术(TEA)或锁定钢板切开复位内固定术(ORIF)治疗老年肱骨远端关节内骨折的疗效和并发症发生率。

数据来源

使用了PubMed、Embase和Cochrane数据库。检索涵盖截至2013年6月的出版物。文章筛选由2位作者独立进行,分歧通过共识解决。

研究选择

符合纳入标准的研究为观察性队列研究或随机对照试验,评估采用初次TEA或锁定钢板ORIF治疗老年肱骨远端骨折患者的功能和影像学结果及并发症。平均年龄<60岁的研究、TEA的适应证不是急性骨折的研究以及包括非锁定钢板的研究被排除。

数据提取

进行标准化数据提取。使用质量评估工具评估个体研究方法。

数据合成

报告功能结果的描述性统计。对并发症发生率进行荟萃分析和回归分析。

结论

一项系统评价和荟萃分析显示,TEA和ORIF治疗老年肱骨远端骨折产生相似的功能结果评分和活动范围。虽然ORIF后主要并发症和再次手术率有升高趋势,但无统计学意义。研究方法的质量总体较弱。需要进行包括前瞻性试验和成本分析在内的进一步研究,以更好地明确ORIF与TEA在这些损伤治疗中的作用。

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