Wax Mark K
Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Sciences University, Portland, Oregon, U.S.A.
Laryngoscope. 2014 Mar;124 Suppl 1:S1-12. doi: 10.1002/lary.24569.
OBJECTIVES/HYPOTHESIS: Free tissue transfer has success rates greater than 95%. Approximately 10% will require reexploration for vascular compromise. Return to the operating room within 48 hours yields the highest rate of successful salvage. Our aim was to determine whether an implantable Doppler used for intraoperative/postoperative monitoring would 1) alter the pattern of detecting flap failure and 2) alter the overall incidence of flap survival.
Prospective analysis.
Generic and study specific data was collected. Note was made at the end of the case if revision of the vascular anastomosis was performed. Data was collected for flap outcomes in the postoperative period.
A total of 1,236 free tissues transfers from 2001 through 2011 were analyzed. Ninety-four were outside the head and neck or the Doppler was not used/inadvertently discontinued. A total of 1,142 flaps make up the study cohort. One hundred thirty-four (11.7%) intraoperative flow problems were detected, all successfully revised. Of these, 15 (11%) required postoperative revision and five (33%) were successfully salvaged, with an overall survival 93%. A total of 1,008 flaps did not require intraoperative revision, 62 required reexploration (6.1%), and 38 (61%) were salvaged. The overall survival was 97.6%. There were eight false positive (no intervention) and 10 false negatives. Sensitivity was 87% with specificity 99%.
Intraoperative Doppler's increase the detection of immediate/incipient vascular problems. Patients requiring revision in the operating room require revision more often in the postoperative period (P = .03) and are less likely to have successful salvage and a lower flap survival rate (P = .05).
目的/假设:游离组织移植成功率超过95%。约10%的病例因血管并发症需要再次手术探查。48小时内返回手术室进行挽救的成功率最高。我们的目的是确定用于术中/术后监测的植入式多普勒是否会:1)改变皮瓣失败的检测模式;2)改变皮瓣存活的总体发生率。
前瞻性分析。
收集一般数据和研究特定数据。手术结束时记录是否对血管吻合进行了修复。收集术后皮瓣结果的数据。
分析了2001年至2011年共1236例游离组织移植病例。94例不在头颈部或未使用多普勒/无意中停用了多普勒。共有1142例皮瓣组成研究队列。检测到134例(11.7%)术中血流问题,均成功修复。其中,15例(11%)术后需要再次修复,5例(33%)成功挽救,总体存活率为93%。共有1008例皮瓣术中无需修复,62例(6.1%)需要再次探查,38例(61%)成功挽救。总体存活率为97.6%。有8例假阳性(未干预)和10例假阴性。敏感性为87%,特异性为99%。
术中使用多普勒可增加对即刻/早期血管问题的检测。术中需要在手术室进行修复的患者术后更常需要再次修复(P = 0.03),且成功挽救的可能性较小,皮瓣存活率较低(P = 0.05)。