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因摄入光烟草导致的急性呼吸衰竭。

Acute respiratory failure due to Nicotiana glauca ingestion.

作者信息

Ntelios D, Kargakis M, Topalis T, Drouzas A, Potolidis E

机构信息

Department of Internal Medicine, Volos General Hospital, Volos, Greece.

Intensive Care Unit, Volos General Hospital, Volos, Greece.

出版信息

Hippokratia. 2013 Apr;17(2):183-4.

Abstract

BACKGROUND

A variety of organisms produce potent toxins that impact human health through compromising respiratory function.

CASE REPORT

We describe a rare case of abrupt respiratory failure afterNicotiana glaucaingestion in a previously healthy sixty years old female patient. She presented complaining for gait instability and malaise after ingestion of cooked leaves of the wild plant and two hours after the onset she developed respiratory failurefor which she was intubated and mechanically ventilated for two days. The patient fully recovered and was discharged from the hospital.

CONCLUSION

Anabasine, the plant's main active ingredient, can cause severe systemic intoxication due to its nicotinic receptor agonist action with respiratory muscle paralysis being the main effect.

摘要

背景

多种生物会产生强效毒素,通过损害呼吸功能影响人类健康。

病例报告

我们描述了一例罕见病例,一名60岁既往健康的女性患者在摄入黄花烟草后突然发生呼吸衰竭。她在食用了这种野生植物的煮熟叶子后出现步态不稳和不适的症状,发病两小时后出现呼吸衰竭,为此她接受了插管并进行了两天的机械通气。患者完全康复并出院。

结论

该植物的主要活性成分新烟草碱可因其烟碱受体激动剂作用导致严重的全身中毒,主要影响是呼吸肌麻痹。

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