Joseph Bindhu, Supe Sanjay S, Ramachandra Aruna
Department of Radiation Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Hosur Road, Bangalore, 560 029 Karnataka, India.
Rep Pract Oncol Radiother. 2010 Jul 6;15(4):93-7. doi: 10.1016/j.rpor.2010.05.002.
The Cyberknife represents a new, frameless stereotactic radiosurgery system which efficiently incorporates advance robotics with computerized image reconstruction to allow highly conformal image guided radiation delivery. This review focus is on the pros and cons of this new radiotherapy tool, its current indications, safety profile and future directions. A literature search of Medline, Pubmed, Biomed, Medscape and Cancer lit database were referred to retrieve relevant data/information. The authors conclude that the use of this system offers an invaluable solution to the treatment of selective tumours/lesions located close to critical structures, salvage of recurrent and metastatic lesions and potential of treatment of selective early stage malignancies like the carcinoma prostate and lung. However, it is still too premature, with insufficient follow up data to advocate it as the treatment of choice in any set up. There are several radiobiological issues that also remain in the greyzone.
射波刀代表了一种新型的无框架立体定向放射外科系统，它有效地将先进的机器人技术与计算机图像重建相结合，以实现高度适形的图像引导放射治疗。本综述聚焦于这种新的放射治疗工具的优缺点、当前适应症、安全性概况及未来发展方向。通过检索医学文献数据库（Medline、Pubmed、Biomed、Medscape和Cancer lit）来获取相关数据/信息。作者得出结论，该系统的使用为治疗位于关键结构附近的选择性肿瘤/病变、挽救复发和转移性病变以及治疗前列腺癌和肺癌等选择性早期恶性肿瘤提供了宝贵的解决方案。然而，现在提倡将其作为任何情况下的首选治疗方法还为时过早，因为随访数据不足。还有几个放射生物学问题也仍不明确。
