Filippi Andrea Riccardo, Franco Pierfrancesco, Ciammella Patrizia
Radiation Oncology, Department of Oncology, University of Torino, Torino, Italy.
Radiation Oncology Department, Tomotherapy Unit, Ospedale Regionale 'U. Parini', AUSL Valle d'Aosta, Aosta, Italy.
Rep Pract Oncol Radiother. 2012 Jul 19;17(5):246-50. doi: 10.1016/j.rpor.2012.05.003. eCollection 2012 Sep.
The role of radiotherapy is well established in combined modality programs for early stage Hodgkin's lymphoma, but still debated with regards to late toxicity issues. Modern radiotherapy prescribing attitudes include lower doses and smaller fields, together with the implementation of sophisticated and dedicated delivery techniques. Aim of this review is to briefly discuss the current role of radiotherapy in this field and the potential future developments. Major trials conducted in recent years in early stage Hodgkin's lymphoma are critically reviewed and discussed with a focus on radiotherapy-related issues and with an attention to current treatment options by a "young" radiation oncologists' perspective.
放射治疗在早期霍奇金淋巴瘤的综合治疗方案中的作用已得到充分确立,但在晚期毒性问题方面仍存在争议。现代放射治疗的处方理念包括降低剂量、缩小照射野,同时采用先进且专门的放疗技术。本综述的目的是简要讨论放射治疗在该领域的当前作用以及未来可能的发展。对近年来早期霍奇金淋巴瘤进行的主要试验进行了批判性回顾和讨论,重点关注与放射治疗相关的问题,并从一位“年轻”放射肿瘤学家的角度关注当前的治疗选择。