Tsuji Mayumi, Yasuda Tetsuyuki, Kaneto Hideaki, Matsuoka Taka-Aki, Hirose Takahisa, Kawamori Ryuzo, Iseki Masako, Shimomura Iichiro, Shibata Masahiko
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Division of Diabetes, Metabolism, and Endocrinology, Department of Medicine, Toho University School of Medicine, 5-21-16 Ohmorinishi, Ota-ku, Tokyo 143-8540, Japan.
Pain Res Treat. 2013;2013:318352. doi: 10.1155/2013/318352. Epub 2013 Nov 26.
Although chronic pain due to diabetic neuropathy, defined as painful diabetic neuropathy (PDN), is a debilitating and distressing complication of diabetes, epidemiological data on PDN has been scarce, especially in Asia. We evaluated the prevalence of Japanese PDN and its impact on their quality of life (QOL) and metnal state. In addition, we examined to which extent physicians are aware of patients' PDN. A total of 298 patients with diabetes were found to be eligible for the study. We revealed that substantial percentage (22.1%) of Japanese diabetic patients had PDN and that PDN had negative effect on patients' QOL and mental state. However, physicians were aware of PDN in only 36.4% of patients with the condition. To the best of our knowledge, this is the first report showing the extent of physicians' awareness of patients' PDN. In conclusion, physicians treating diabetes need to be more aware of patients' PDN in everyday clinical practice to prevent the progression of PDN and improve the patients' QOL and mental state.
尽管由糖尿病神经病变引起的慢性疼痛，即疼痛性糖尿病神经病变（PDN），是糖尿病一种使人衰弱且令人痛苦的并发症，但关于PDN的流行病学数据一直很匮乏，尤其是在亚洲。我们评估了日本PDN的患病率及其对患者生活质量（QOL）和精神状态的影响。此外，我们还调查了医生对患者PDN的知晓程度。共有298名糖尿病患者符合该研究的条件。我们发现，相当比例（22.1%）的日本糖尿病患者患有PDN，且PDN对患者的QOL和精神状态有负面影响。然而，医生仅知晓36.4%患有该疾病的患者的PDN情况。据我们所知，这是第一份展示医生对患者PDN知晓程度的报告。总之，治疗糖尿病的医生在日常临床实践中需要更加关注患者的PDN情况，以防止PDN病情进展并改善患者的QOL和精神状态。
